Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | PKM | P14618 | 5/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13681015 | 0.85 | ALDH1A1 (0.46) | ALDH1A1MAPTPKMHTTHSD17B10 | |
| SCHEMBL13680887 | 0.83 | ALDH1A1 (0.46) | ALDH1A1MAPTPKMHTTHSD17B10 | |
| SCHEMBL13680864 | 0.83 | ALDH1A1 (0.63) | ALDH1A1MAPTPKMHTTHSD17B10 | |
| SCHEMBL13680866 | 0.83 | ALDH1A1 (0.60) | ALDH1A1MAPTPKMHTTHSD17B10 | |
| SCHEMBL13680882 | 0.82 | KDM4E (0.60) | ALDH1A1MAPTPKMHTTHSD17B10 | |
| SCHEMBL13680865 | 0.82 | SOS1 (0.56) | ALDH1A1MAPTPKMHTTHSD17B10 | |
| SCHEMBL13680886 | 0.81 | CYP2A6 (0.64) | ALDH1A1MAPTPKMHTTHSD17B10 | |
| SCHEMBL13680979 | 0.80 | ALDH1A1 (0.47) | ALDH1A1MAPTPKMHTTHSD17B10 | |
| SCHEMBL13681302 | 0.79 | ALDH1A1 (0.40) | ALDH1A1MAPTPKMHTTHSD17B10 | |
| SCHEMBL13680869 | 0.79 | PRMT1 (0.46) | ALDH1A1MAPTPKMHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |