Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | PKM | P14618 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680887 | 0.83 | ALDH1A1 (0.46) | ALDH1A1NPSR1KDM4EMAPTPKM | |
| SCHEMBL13680866 | 0.83 | ALDH1A1 (0.60) | ALDH1A1NPSR1KDM4EMAPTPKM | |
| SCHEMBL13680859 | 0.83 | ALDH1A1 (0.60) | ALDH1A1NPSR1KDM4EMAPTPKM | |
| SCHEMBL9867707 | 0.83 | ALDH1A1 (0.57) | ALDH1A1NPSR1KDM4EMAPTPKM | |
| SCHEMBL13680865 | 0.83 | SOS1 (0.56) | ALDH1A1NPSR1KDM4EMAPTPKM | |
| SCHEMBL13680979 | 0.81 | ALDH1A1 (0.47) | ALDH1A1NPSR1KDM4EMAPTPKM | |
| SCHEMBL13681302 | 0.80 | ALDH1A1 (0.40) | ALDH1A1NPSR1KDM4EMAPTPKM | |
| SCHEMBL13680869 | 0.80 | PRMT1 (0.46) | ALDH1A1NPSR1KDM4EMAPTPKM | |
| SCHEMBL13680882 | 0.80 | KDM4E (0.60) | ALDH1A1NPSR1KDM4EMAPTPKM | |
| SCHEMBL13680867 | 0.80 | ALDH1A1 (0.63) | ALDH1A1NPSR1KDM4EMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |