Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | HTT | P42858 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5043750 | 0.84 | SOS1 (0.59) | SOS1MEN1KMT2AL3MBTL1HTR6 | |
| SCHEMBL13680864 | 0.83 | ALDH1A1 (0.63) | MEN1KMT2AL3MBTL1ALDH1A1HTT | |
| SCHEMBL13680859 | 0.82 | ALDH1A1 (0.60) | MEN1KMT2AL3MBTL1HTR6ALDH1A1 | |
| SCHEMBL5043758 | 0.80 | ALDH1A1 (0.68) | SOS1MEN1KMT2AL3MBTL1HTR6 | |
| SCHEMBL624327 | 0.78 | ALDH1A1 (0.60) | SOS1MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL282163 | 0.77 | SOS1 (0.66) | SOS1MEN1KMT2AL3MBTL1HTR6 | |
| SCHEMBL13681020 | 0.76 | ALDH1A1 (0.40) | SOS1MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL10000785 | 0.76 | SOS1 (0.69) | SOS1MEN1KMT2AL3MBTL1HTR6 | |
| SCHEMBL624093 | 0.76 | ALDH1A1 (0.65) | SOS1MEN1KMT2AL3MBTL1HTR6 | |
| SCHEMBL13680886 | 0.75 | CYP2A6 (0.64) | ALDH1A1HTTMAPTPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |