Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3074282 | 0.76 | KDM4E (0.48) | KDM4EPKMMAPTALDH1A1HSD17B10 | |
| SCHEMBL3823188 | 0.76 | KDM4E (0.48) | KDM4EPKMMAPTALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL3821911 | 0.75 | CYP2A6 (0.48) | KDM4EPKMMAPTALDH1A1HSD17B10 | |
| SCHEMBL15008586 | 0.73 | KDM4E (0.48) | KDM4EPKMMAPTALDH1A1HSD17B10 | |
| SCHEMBL423483 | 0.71 | MAPT (0.68) | KDM4EPKMMAPTALDH1A1HSD17B10 | |
| SCHEMBL5494804 | 0.71 | PKM (0.46) | PKMMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL4148228 | 0.70 | PRMT6 (0.45) | KDM4EMAPTALDH1A1HSD17B10KMT2A | |
| SCHEMBL13680909 | 0.70 | KDM4E (0.55) | KDM4EPKMMAPTALDH1A1NPSR1 | |
| SCHEMBL13680908 | 0.68 | CYP2A6 (0.55) | KDM4EALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL10211630 | 0.68 | KDM4E (0.46) | KDM4EPKMMAPTALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |