Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SUCNR1 | Q9BXA5 | 6/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | SDCBP | O00560 | 1/20 | 0.39 |
| ▸ | SDC2 | P34741 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6370655 | 0.82 | L3MBTL1 (0.50) | HDAC1HDAC6L3MBTL1NAMPTSDCBP | |
| SCHEMBL13680609 | 0.80 | HDAC1 (0.47) | HDAC1HDAC6L3MBTL1SUCNR1NAMPT | |
| SCHEMBL13681012 | 0.77 | PSMB8 (0.35) | HDAC1HDAC6KDM4EALDH1A1MAPT | |
| SCHEMBL6391730 | 0.75 | KDM4E (0.47) | SUCNR1NAMPTKDM4EALDH1A1MAPT | |
| SCHEMBL694492 | 0.75 | L3MBTL1 (0.53) | HDAC1HDAC6L3MBTL1NAMPTSDCBP | |
| SCHEMBL13681009 | 0.74 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTPKMDDAH1 | |
| SCHEMBL3180689 | 0.74 | L3MBTL1 (0.61) | HDAC1HDAC6L3MBTL1NAMPTSDCBP | |
| SCHEMBL13680875 | 0.74 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTPKMDDAH1 | |
| SCHEMBL3307112 | 0.74 | L3MBTL1 (0.52) | HDAC1L3MBTL1NAMPTSDCBPSDC2 | |
| SCHEMBL13680876 | 0.73 | ALDH1A1 (0.55) | KDM4EALDH1A1MAPTPKMDDAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |