Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.40 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6273154 | 0.84 | MAPT (0.46) | PTPN1PTPN2MEN1KMT2AKDM4E | |
| SCHEMBL6273151 | 0.82 | PTPN1 (0.42) | PTPN1PTPN2MEN1KMT2AKDM4E | |
| SCHEMBL13037456 | 0.82 | PTPN1 (0.42) | PTPN1PTPN2MEN1KMT2AKDM4E | |
| SCHEMBL13037433 | 0.79 | TAAR1 (0.50) | PTPN1PTPN2MEN1KMT2AKDM4E | |
| SCHEMBL6124205 | 0.79 | KDM4E (0.43) | PTPN1PTPN2MEN1KMT2AKDM4E | |
| SCHEMBL13037451 | 0.79 | CYP1A2 (0.41) | PTPN1PTPN2MEN1KMT2AKDM4E | |
| SCHEMBL27489870 | 0.79 | ERCC5 (0.43) | PTPN1PTPN2MEN1KMT2ADCLRE1A | |
| SCHEMBL9812979 | 0.79 | GABRA1 (0.55) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL12084945 | 0.77 | MEN1 (0.52) | PTPN1PTPN2MEN1KMT2AKDM4E | |
| SCHEMBL5306483 | 0.75 | ALOX5 (0.52) | MEN1KMT2AKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7585878-B2 | Benzamide derivative or salt thereof | ASTELLAS PHARMA INC. (JP) | 2009-09-08 | — | — | US | disclosed |