Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.43 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | GLS2 | Q9UI32 | 1/20 | 0.41 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.41 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12834883 | 0.85 | PTPN1 (0.36) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13037433 | 0.84 | TAAR1 (0.50) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL27668695 | 0.84 | GLS (0.40) | MAPTGLSGLS2DCLRE1ADCLRE1B | |
| SCHEMBL13681900 | 0.84 | PTPN1 (0.45) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6273151 | 0.84 | PTPN1 (0.42) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13037456 | 0.84 | PTPN1 (0.42) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL12834902 | 0.83 | GLS (0.36) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL26682283 | 0.83 | HSD17B1 (0.50) | CYP1A2ERN1HSD17B1 | |
| SCHEMBL764200 | 0.81 | ALDH1A1 (0.41) | ALDH1A1GLSGLS2NPC1RAB9A | |
| SCHEMBL6124205 | 0.81 | KDM4E (0.43) | MAPTMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385036-A1 | N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | Toyama Chemical Co., Ltd. (JP) | 2011-11-09 | — | — | EP | disclosed |
| EP-1567509-A2 | BIPHENYL COMPOUNDS WHICH ACTIVATE PPAR-GAMMA TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004048351-A2 | BIPHENYL COMPOUNDS WHICH ACTIVATE PPAR-GAMMA TYPE RECEPTORS AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-06-10 | — | — | WO | disclosed |