Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10801866 | 0.78 | HTR7 (0.54) | HTR7 | |
| SCHEMBL10799798 | 0.76 | HTR7 (0.46) | HTR7 | |
| SCHEMBL10804764 | 0.75 | HTR7 (0.62) | HTR7 | |
| SCHEMBL26553449 | 0.75 | CREBBP (0.43) | HTR7 | |
| SCHEMBL10806301 | 0.75 | — | — | |
| SCHEMBL10799812 | 0.73 | KDM4E (0.41) | HTR7 | |
| SCHEMBL16200125 | 0.72 | HTR7 (0.38) | HTR7 | |
| SCHEMBL10804904 | 0.72 | HTR7 (0.49) | HTR7 | |
| SCHEMBL22429129 | 0.72 | HTR6 (0.33) | HTR6HTR7 | |
| SCHEMBL7084525 | 0.71 | HTR7 (0.49) | HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589199-B2 | Substituted piperazines | CHEMOCENTRYX, INC. (US) | 2009-09-15 | — | — | US | disclosed |