Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.62 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2075612 | 0.90 | HTR2A (0.61) | HTR7SOS1HTR1AHTR2A | |
| SCHEMBL10806301 | 0.86 | — | — | |
| SCHEMBL10801866 | 0.85 | HTR7 (0.54) | HTR7 | |
| SCHEMBL7084525 | 0.84 | HTR7 (0.49) | HTR7 | |
| SCHEMBL16200125 | 0.77 | HTR7 (0.38) | HTR7 | |
| SCHEMBL26553449 | 0.77 | CREBBP (0.43) | HTR7 | |
| SCHEMBL10804904 | 0.77 | HTR7 (0.49) | HTR7 | |
| SCHEMBL13683115 | 0.75 | HTR6 (0.39) | HTR7 | |
| SCHEMBL31164693 | 0.75 | PNMT (0.39) | HTR7 | |
| SCHEMBL10804878 | 0.75 | HTR7 (0.79) | HTR7HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0086422-B1 | PHARMACOLOGICALLY ACTIVE PYRAZOLO(4,3-C)PYRIDINES | GRUPPO LEPETIT S.p.A. (IT) | 1987-09-30 | — | — | EP | disclosed |