Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 19/20 | 0.83 |
| ▸ | HTR1A | P08908 | 8/20 | 0.83 |
| ▸ | HTR1D | P28221 | 8/20 | 0.83 |
| ▸ | HTR1B | P28222 | 8/20 | 0.83 |
| ▸ | HTR2C | P28335 | 6/20 | 0.83 |
| ▸ | DRD2 | P14416 | 6/20 | 0.83 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.83 |
| ▸ | DRD3 | P35462 | 6/20 | 0.83 |
| ▸ | HTR7 | P34969 | 5/20 | 0.83 |
| ▸ | HTR4 | Q13639 | 5/20 | 0.83 |
| ▸ | HTR2A | P28223 | 5/20 | 0.83 |
| ▸ | DRD1 | P21728 | 1/20 | 0.83 |
| ▸ | DRD4 | P21917 | 1/20 | 0.83 |
| ▸ | HTR2B | P41595 | 5/20 | 0.82 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.82 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.82 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.82 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.82 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29386932 | 0.91 | HTR6 (1.00) | HTR6HTR1AHTR1DHTR1BHTR2C | |
| SCHEMBL194700 | 0.91 | HTR6 (1.00) | HTR6HTR1AHTR1DHTR1BHTR2C | |
| Hydrochloric Acid SCHEMBL6977773 | 0.90 | HTR6 (1.00) | HTR6HTR1AHTR1DHTR1BHTR2C | |
| SCHEMBL29496144 | 0.81 | HTR6 (1.00) | HTR6HTR1AHTR1DHTR1BHTR2C | |
| SCHEMBL1136525 | 0.81 | HTR6 (1.00) | HTR6HTR1AHTR1DHTR1BHTR2C | |
| SCHEMBL7199110 | 0.79 | HTR6 (0.82) | HTR6HTR1AHTR1DHTR1BHTR2C | |
| SCHEMBL194699 | 0.77 | HTR6 (0.76) | HTR6HTR1AHTR1DHTR1BHTR2C | |
| SCHEMBL4801548 | 0.77 | GHSR (1.00) | HTR6HTR1AHTR1DHTR1BHTR2C | |
| SCHEMBL4801555 | 0.77 | GHSR (1.00) | HTR6HTR1AHTR1DHTR1BHTR2C | |
| SCHEMBL6983122 | 0.76 | HTR6 (0.65) | HTR6HTR1AHTR1DHTR1BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592457-B2 | 3-aryl-3-methyl-quinoline-2, 4-diones, preparation method thereof, and pharmaceutical composition containing the same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-09-22 | — | — | US | disclosed |