Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 8/20 | 0.52 |
| ▸ | LTB4R2 | Q9NPC1 | 7/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MLYCD | O95822 | 1/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | F13A1 | P00488 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | TGM1 | P22735 | 1/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13181407 | 0.91 | LTB4R (0.56) | LTB4RLTB4R2ALDH1A1MLYCDNPY5R | |
| SCHEMBL23291183 | 0.89 | LTB4R (0.54) | LTB4RLTB4R2OPRM1OPRD1OPRK1 | |
| SCHEMBL206739 | 0.86 | LTB4R (0.52) | LTB4RLTB4R2OPRM1OPRD1OPRK1 | |
| SCHEMBL3863448 | 0.86 | LTB4R (0.52) | LTB4RLTB4R2ALDH1A1MLYCDNPY5R | |
| SCHEMBL8233693 | 0.84 | LTB4R (0.50) | LTB4RLTB4R2OPRM1OPRD1OPRK1 | |
| SCHEMBL206963 | 0.84 | LTB4R (0.50) | LTB4RLTB4R2ALDH1A1MLYCDNPY5R | |
| SCHEMBL3859118 | 0.84 | LTB4R (0.50) | LTB4RLTB4R2OPRM1OPRD1OPRK1 | |
| SCHEMBL7367495 | 0.83 | ALDH1A1 (0.58) | ALDH1A1F13A1TGM2TGM1 | |
| SCHEMBL14357352 | 0.83 | LTB4R (0.52) | LTB4RLTB4R2OPRM1MLYCD | |
| SCHEMBL10603208 | 0.81 | APP (0.50) | LTB4RLTB4R2OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592331-B2 | Macrocyclic factor VIIa inhibitors useful as anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-09-22 | — | — | US | disclosed |