Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNLIP | P16233 | 3/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 2/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.48 |
| ▸ | PGR | P06401 | 2/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12902001 | 0.90 | PNLIP (0.53) | PNLIPFFAR1CRHBPCRHR2PGR | |
| SCHEMBL27676843 | 0.73 | MEN1 (0.74) | PNLIPFFAR1CRHBPCRHR2STK39 | |
| SCHEMBL13744380 | 0.73 | DHODH (0.55) | PNLIPCRHBPCRHR2PGRNR1H4 | |
| SCHEMBL3472646 | 0.73 | BCL2L1 (0.57) | PNLIPPGRNR1H4STK39 | |
| SCHEMBL9843543 | 0.71 | ALDH1A1 (0.52) | SMN1; SMN2MAPTLMNAMEN1HTT | |
| SCHEMBL4350025 | 0.70 | MEN1 (0.59) | PNLIPFFAR1SIRT6MAPK1SMN1; SMN2 | |
| SCHEMBL8306391 | 0.70 | FFAR1 (0.65) | FFAR1CRHBPCRHR2PGRNR1H4 | |
| SCHEMBL31315570 | 0.70 | FFAR1 (0.80) | FFAR1CRHBPCRHR2PGRSMN1; SMN2 | |
| SCHEMBL27676573 | 0.70 | FFAR1 (0.80) | FFAR1CRHBPCRHR2PGRSMN1; SMN2 | |
| SCHEMBL6691053 | 0.69 | MEN1 (0.61) | PNLIPFFAR1MAPK1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592315-B2 | Peptide viral entry inhibitors | SCHERING CORPORATION (US) | 2009-09-22 | — | — | US | disclosed |