Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TLR4 | O00206 | 3/20 | 0.44 |
| ▸ | TLR2 | O60603 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30072571 | 0.79 | HSD17B10 (0.52) | ALDH1A1TDP1MAPTNPSR1TLR4 | |
| SCHEMBL25191976 | 0.79 | TDP1 (0.47) | ALDH1A1TDP1XDHMAPTATM | |
| SCHEMBL443483 | 0.79 | HSD17B10 (0.52) | ALDH1A1TDP1MAPTNPSR1TLR4 | |
| SCHEMBL6491051 | 0.79 | MAPT (0.56) | ALDH1A1TDP1MAPTNPSR1MEN1 | |
| SCHEMBL28940780 | 0.79 | HTT (0.48) | ALDH1A1TDP1NPSR1TSHRHTT | |
| SCHEMBL11126859 | 0.79 | ALDH1A1 (0.52) | ALDH1A1TDP1XDHMAPTATM | |
| SCHEMBL18956918 | 0.79 | HSPB1 (0.44) | ALDH1A1TDP1XDHMAPTATM | |
| SCHEMBL30218255 | 0.78 | KMT2A (0.60) | ALDH1A1TDP1XDHMAPTMEN1 | |
| SCHEMBL8903443 | 0.77 | MAPT (0.49) | ALDH1A1TDP1MAPTATMTLR4 | |
| SCHEMBL2271210 | 0.76 | SMN1; SMN2 (0.54) | ALDH1A1XDHMAPTNPSR1TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415641-A1 | Substituted glutaramic acids and derivatives | ROHM AND HAAS COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |
| EP-0415642-A1 | Glutarimides | ROHM AND HAAS COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |