SCHEMBL136836

SCHEMBL136836

FC(F)(F)c1ccc2nc(-c3ccc(-c4nc5ccc(C(F)(F)F)cc5nc4-c4ccccc4)c(-c4nc5ccc(C(F)(F)F)cc5nc4-c4ccccc4)c3)c(-c3ccccc3)nc2c1

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.51
DHFR P00374 13/20 0.49
AKT1 P31749 1/20 0.49
AKT2 P31751 1/20 0.49
DHODH Q02127 1/20 0.48
TYMS P04818 1/20 0.47
ADORA2A P29274 1/20 0.46
ADORA1 P30542 1/20 0.46
DGAT1 O75907 1/20 0.46
KCNH2 Q12809 1/20 0.46
ALDH1A1 P00352 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
KMT2A Q03164 1/20 0.45
ATM Q13315 1/20 0.45
TLR9 Q9NR96 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31070214 0.88 KDM4E (0.64) KDM4EDHFRAKT1AKT2DHODH
SCHEMBL1229501 0.85 KDM4E (0.60) KDM4EDHFRAKT1AKT2DHODH
SCHEMBL12111668 0.82 AKT1 (0.57) KDM4EDHFRAKT1AKT2DHODH
SCHEMBL12111572 0.82 AKT1 (0.57) KDM4EDHFRAKT1AKT2DHODH
SCHEMBL12111632 0.82 AKT1 (0.57) KDM4EDHFRAKT1AKT2DHODH
SCHEMBL12111564 0.82 AKT1 (0.57) KDM4EDHFRAKT1AKT2DHODH
SCHEMBL12111669 0.81 ADORA2A (0.59) KDM4EDHFRAKT1AKT2DHODH
SCHEMBL12111631 0.81 ADORA2A (0.59) KDM4EDHFRAKT1AKT2DHODH
SCHEMBL12111554 0.81 ADORA2A (0.59) KDM4EDHFRAKT1AKT2DHODH
SCHEMBL12111571 0.81 ADORA2A (0.59) KDM4EDHFRAKT1AKT2DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11145820-B2 Organic optoelectronic device and display device SAMSUNG SDI CO., LTD. (KR) 2021-10-12 US disclosed
US-10326091-B2 Organic electrochemical device, and method for manufacturing same LG CHEM, LTD. (KR) 2019-06-18 US disclosed
US-10153452-B2 Organic light emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-12-11 US disclosed
US-10074810-B2 Organic optoelectric device and display device SAMSUNG SDI CO., LTD. (KR) 2018-09-11 US disclosed
US-20180114939-A1 ORGANIC LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2018-04-26 US disclosed
US-20170222158-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2017-08-03 US disclosed
US-9530970-B2 Benzimidazole compound, organic photoelectric device including the same, and display element including the same CHEIL INDUSTRIES, INC. (KR) 2016-12-27 US disclosed
EP-2431445-B1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE COMPRISING SAME CHEIL IND INC (KR) 2016-11-23 EP disclosed
US-20160126471-A1 ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-05-05 US disclosed
US-9299937-B2 Active layer, organic photovoltaic cell comprising the same and manufacturing method thereof LG CHEM, LTD. (KR) 2016-03-29 US disclosed
US-20110253994-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY DEVICE INCLUDING THE SAME CHEIL INDUSTRIES, INC. (KR) 2011-10-20 US disclosed
EP-2344611-A1 BENZIMIDAZOLE COMPOUNDS AND ORGANIC PHOTOELECTRIC DEVICE WITH THE SAME Cheil Industries Inc. (KR) 2011-07-20 EP disclosed
US-20110042654-A1 Organic compound, and organic photoelectric device comprising the same CHEIL INDUSTRIES, INC. (KR) 2011-02-24 US disclosed
US-20100276673-A1 Organic compound, and organic photoelectric device including the same CHEIL INDUSTRIES, INC. (KR) 2010-11-04 US disclosed
US-20100176718-A1 Polymer and organic photoelectric device including the same CHEIL INDUSTRIES, INC. (KR) 2010-07-15 US disclosed
WO-2010044607-A1 BENZIMIDAZOLE COMPOUNDS AND ORGANIC PHOTOELECTRIC DEVICE WITH THE SAME CHEIL INDUSTRIES INC. (KR) 2010-04-22 WO disclosed
WO-2006062323-A1 ELECTROLUMINESCENT POLYMER HAVING 9-FLUOREN-2-YL-9-ARYL-2,7-FLUORENYL UNIT AND ELECTROLUMINESCENT DEVICE MANUFACTURED USING THE SAME SK CORPORATION (KR) 2006-06-15 WO disclosed
US-20060121314-A1 Electroluminescent polymer having 9-fluoren-2-yl-9-aryl-2,7-fluorenyl unit and electroluminescent device manufactured using the same SK CORPORATION (KR) 2006-06-08 US disclosed
US-20030157367-A1 Blue light-emitting polymer containing 9, 10-diphenylanthracene moiety and electroluminescent device using the same SK CORPORATION 2003-08-21 US disclosed
WO-2003040255-A1 BLUE LIGHT-EMITTING POLYMER CONTAINING 9,10-DIPHENYLANTHRACENE MOIETY AND ELECTROLUMINESCENT DEVICE USING THE SAME SK CORPORATION (KR) 2003-05-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110042654-A1 Organic compound, and organic photoelectric device comprising the same PPOX, OR10J3, OCIAD1 KDM4E 1871/4885DHFR 2610/4885AKT1 2317/4885
US-20170222158-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OCIAD2, OCIAD1, AOX1 KDM4E 3418/4885DHFR 3479/4885AKT1 1660/4885
US-20110253994-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY DEVICE INCLUDING THE SAME OR10J3, OR51E2, AOX1 KDM4E 3158/4885DHFR 675/4885AKT1 3748/4885
US-20100276673-A1 Organic compound, and organic photoelectric device including the same OR10J3, EPB41, CACNA2D4 KDM4E 953/4885DHFR 4252/4885AKT1 1566/4885
US-11145820-B2 Organic optoelectronic device and display device OCIAD2, OCIAD1, AOX1 KDM4E 3418/4885DHFR 3479/4885AKT1 1660/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.