SCHEMBL1229501

SCHEMBL1229501

FC(F)(F)c1ccc2nc(-c3cc(-c4nc5ccc(C(F)(F)F)cc5nc4-c4ccccc4)cc(-c4nc5ccc(C(F)(F)F)cc5nc4-c4ccccc4)c3)c(-c3ccccc3)nc2c1

nearest known ligand 0.60

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.60
DHFR P00374 14/20 0.55
TYMS P04818 1/20 0.53
ALDH1A1 P00352 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
KMT2A Q03164 1/20 0.53
ATM Q13315 1/20 0.53
TLR9 Q9NR96 1/20 0.53
AKT1 P31749 1/20 0.53
AKT2 P31751 1/20 0.53
NPBWR1 P48145 1/20 0.51
DHODH Q02127 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31070214 0.97 KDM4E (0.64) KDM4EDHFRTYMSALDH1A1L3MBTL1
SCHEMBL12352239 0.91 KDM4E (0.69) KDM4EDHFRTYMSALDH1A1L3MBTL1
SCHEMBL22148688 0.91 KMT2A (0.69) KDM4EDHFRTYMSALDH1A1L3MBTL1
SCHEMBL21563928 0.89 TLR9 (0.49) KDM4EDHFRTYMSTLR9
SCHEMBL17450954 0.89 DHFR (0.50) KDM4EDHFRTYMS
SCHEMBL23052851 0.88 KDM4E (0.48) KDM4EDHFRTYMSAKT1AKT2
SCHEMBL12111668 0.87 AKT1 (0.57) KDM4EDHFRTYMSALDH1A1L3MBTL1
SCHEMBL12111564 0.87 AKT1 (0.57) KDM4EDHFRTYMSALDH1A1L3MBTL1
SCHEMBL12111572 0.87 AKT1 (0.57) KDM4EDHFRTYMSALDH1A1L3MBTL1
SCHEMBL12111632 0.87 AKT1 (0.57) KDM4EDHFRTYMSALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12048175-B2 Organic electroluminescent device KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2024-07-23 US disclosed
US-20240032422-A1 LIGHT-EMITTING MATERIAL, COMPOUND, LONG-PERSISTENT PHOSPHOR AND LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2024-01-25 US disclosed
US-11778904-B2 Composition of matter for use in organic light-emitting diodes KYULUX, INC. (JP) 2023-10-03 US disclosed
EP-3404734-B1 ORGANIC ELECTROLUMINESCENT ELEMENT, ELEMENT GROUP, METHOD FOR MANUFACTURING ORGANIC ELECTROLUMINESCENT ELEMENT, AND METHOD FOR CONTROLLING EMISSION WAVELENGTH OF ORGANIC ELECTROLUMINESCENT ELEMENT UNIV KYUSHU NAT UNIV CORP (JP) 2023-08-30 EP disclosed
US-20230225147-A1 ORGANIC LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2023-07-13 US disclosed
US-20230157149-A1 ORGANIC-INORGANIC PEROVSKITE, FILM, LIGHT-EMITTING FILM, DELAYED FLUORESCENCE-EMITTING FILM, LIGHT-EMITTING ELEMENT, AND METHOD FOR PRODUCING LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2023-05-18 US disclosed
US-11588118-B2 Composition of matter for use in organic light-emitting diodes KYULUX, INC. (JP) 2023-02-21 US disclosed
US-11575088-B2 Composition of matter for use in organic light-emitting diodes KYULUX, INC. (JP) 2023-02-07 US disclosed
EP-3171421-B1 ORGANIC LIGHT-EMITTING ELEMENT UNIV KYUSHU NAT UNIV CORP (JP) 2023-01-25 EP disclosed
WO-2023286670-A1 BORON-CONTAINING COMPOUND, LIGHT-EMITTING MATERIAL AND LIGHT-EMITTING ELEMENT USING SAME 国立大学法人九州大学 2023-01-19 WO disclosed
WO-2006043681-A1 COMPOSITION FOR CONDUCTIVE MATERIALS, CONDUCTIVE MATERIAL, CONDUCTIVE LAYER, ELECTRONIC DEVICE, AND ELECTRONIC EQUIPMENT SEIKO EPSON CORPORATION (JP) 2006-04-27 WO disclosed
WO-2006043680-A1 COMPOSITION FOR CONDUCTIVE MATERIALS, CONDUCTIVE MATERIAL, CONDUCTIVE LAYER, ELECTRONIC DEVICE, AND ELECTRONIC EQUIPMENT SEIKO EPSON CORPORATION (JP) 2006-04-27 WO disclosed
WO-2006025612-A1 MATERIAL COMPOSITION FOR CONDUCTIVE LAYERS IN ELECTRONIC DEVICES SEIKO EPSON CORPORATION (JP) 2006-03-09 WO disclosed
WO-2006025611-A1 MATERIAL COMPOSITION FOR CONDUCTIVE LAYERS IN ELECTRONIC DEVICES SEIKO EPSON CORPORATION (JP) 2006-03-09 WO disclosed
WO-2006022439-A1 COMPOSITION FOR CONDUCTIVE MATERIALS COMPRISING TETRA ACRYLATE FUNCTIONALISED ARYLAMINES, CONDUCTIVE MATERIAL AND LAYER, ELECTRONIC DEVICE EQUIPMENT SEIKO EPSON CORPORATION (JP) 2006-03-02 WO disclosed
WO-2005041321-A1 PURIFICATION OF HOLE TRANSPORTING MATERIAL BY MEANS OF ULTRAFILTRATION AND ION EXCHANGE CHROMATOGRAPHY SEIKO EPSON CORPORATION (JP) 2005-05-06 WO disclosed
US-20050062012-A1 Hole transport material and method of manufacturing the hole transport material SEIKO EPSON CORPORATION (JP) 2005-03-24 US disclosed
US-20050012450-A1 Light emitting material, method of manufacturing the light emitting material and method of manufacturing light emitting layer SEIKO EPSON CORPORATION (JP) 2005-01-20 US disclosed
EP-1484382-A1 Light emitting material, method of manufacturing the light emitting material and method of manufacturing light emitting layer SEIKO EPSON CORPORATION (JP) 2004-12-08 EP disclosed
EP-1482576-A2 Hole transport material and method of manufacturing the hole transport material SEIKO EPSON CORPORATION (JP) 2004-12-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240032422-A1 LIGHT-EMITTING MATERIAL, COMPOUND, LONG-PERSISTENT PHOSPHOR AND LIGHT-EMITTING ELEMENT NR2E3, CRY1, ESR1 KDM4E 4118/4885DHFR 2432/4885TYMS 3839/4885
US-11778904-B2 Composition of matter for use in organic light-emitting diodes CRY2, SLCO1B3, NDUFV3 KDM4E 4691/4885DHFR 168/4885TYMS 2234/4885
US-20230157149-A1 ORGANIC-INORGANIC PEROVSKITE, FILM, LIGHT-EMITTING FILM, DELAYED FLUORESCENCE-EMITTING FILM, LIGHT-EMITTING ELEMENT, AND METHOD FOR PRODUCING LIGHT-EMITTING ELEMENT ECE1, ECE2, ESR1 KDM4E 374/4885DHFR 4627/4885TYMS 3370/4885
US-11575088-B2 Composition of matter for use in organic light-emitting diodes CRY2, CYBA, ALDH1A2 KDM4E 4556/4885DHFR 380/4885TYMS 2580/4885
US-11588118-B2 Composition of matter for use in organic light-emitting diodes OPRD1, NR1H3, NR1H2 KDM4E 3357/4885DHFR 1977/4885TYMS 3866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.