Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL446497 | 0.80 | MAPT (0.72) | MAPTCYP3A4BLMPMP22ALDH1A1 | |
| SCHEMBL6047059 | 0.79 | MAPT (0.67) | MAPTCYP3A4BLMPMP22ALDH1A1 | |
| Tretazicar SCHEMBL29375352 | 0.75 | MAPT (1.00) | MAPTCYP3A4BLMPMP22ALDH1A1 | |
| Tretazicar SCHEMBL366755 | 0.75 | MAPT (1.00) | MAPTCYP3A4BLMPMP22ALDH1A1 | |
| SCHEMBL5581335 | 0.73 | MAPT (0.78) | MAPTCYP3A4BLMPMP22ALDH1A1 | |
| SCHEMBL13685668 | 0.73 | MAPT (0.78) | MAPTCYP3A4BLMPMP22ALDH1A1 | |
| SCHEMBL6571188 | 0.72 | MAPT (0.68) | MAPTCYP3A4BLMPMP22ALDH1A1 | |
| SCHEMBL3678573 | 0.72 | MAPT (0.72) | MAPTCYP3A4BLMPMP22ALDH1A1 | |
| SCHEMBL27754610 | 0.70 | MAPT (0.68) | MAPTCYP3A4BLMPMP22ALDH1A1 | |
| SCHEMBL31296615 | 0.70 | MAPT (0.60) | MAPTCYP3A4BLMPMP22ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951213-B1 | USE OF ALPHA-HYDROXY CARBONYL COMPOUNDS AS REDUCING AGENTS | MORVUS TECHNOLOGY LTD (GB) | 2012-11-14 | — | — | EP | disclosed |