Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.34 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13684452 | 0.90 | CTSK (0.39) | CTSKPTGER2CYP2C19GAAHSD17B10 | |
| SCHEMBL13127927 | 0.87 | CTSK (0.39) | CTSKPTGER2CYP2C19GAAHSD17B10 | |
| SCHEMBL12584775 | 0.86 | HSD17B10 (0.38) | CTSKPTGER2CYP2C19GAALMNA | |
| SCHEMBL12606651 | 0.83 | HSD17B10 (0.38) | CTSKPTGER2CYP2C19GAALMNA | |
| SCHEMBL13251282 | 0.81 | HSD17B10 (0.37) | CTSKPTGER2CYP2C19GAAHSD17B10 | |
| SCHEMBL8280433 | 0.80 | HSD17B10 (0.36) | CTSKPTGER2CYP2C19GAALMNA | |
| SCHEMBL13127925 | 0.76 | ALDH1A1 (0.46) | GAALMNAHSD17B10TSHRHTT | |
| SCHEMBL8034471 | 0.75 | HSD17B10 (0.40) | CTSKPTGER2CYP2C19HSD17B10TSHR | |
| SCHEMBL8281133 | 0.73 | CTSV (0.37) | CTSK | |
| SCHEMBL14011644 | 0.73 | EP300 (0.45) | CTSKGAAHSD17B10TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592419-B2 | Macrocyclic inhibitors of hepatitis C virus NS3-serine protease | SCHERING CORPORATION (US) | 2009-09-22 | — | — | US | disclosed |