Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.46 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.46 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.38 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7597811 | 0.79 | TSHR (0.62) | TXNRD1TXNRD3TXNRD2TDP1MAPT | |
| SCHEMBL8973665 | 0.79 | TXNRD1 (0.72) | TXNRD1TXNRD3TXNRD2TDP1MAPT | |
| SCHEMBL31050303 | 0.78 | TXNRD1 (0.46) | TXNRD1TXNRD3TXNRD2TDP1MAPT | |
| SCHEMBL3874156 | 0.78 | PDE7A (0.58) | TXNRD1TXNRD3TXNRD2TDP1MAPT | |
| SCHEMBL29593492 | 0.78 | ALDH1A1 (0.59) | TXNRD1TXNRD3TXNRD2TDP1MAPT | |
| SCHEMBL16950944 | 0.78 | TXNRD1 (0.46) | TXNRD1TXNRD3TXNRD2TDP1MAPT | |
| SCHEMBL9017792 | 0.78 | TXNRD1 (0.46) | TXNRD1TXNRD3TXNRD2TDP1MAPT | |
| SCHEMBL8669659 | 0.78 | PDE7A (0.61) | KMT2AMEN1PDE7APDE7BCCR2 | |
| SCHEMBL11144762 | 0.78 | ALDH1A1 (0.59) | TXNRD1TXNRD3TXNRD2TDP1MAPT | |
| SCHEMBL2650807 | 0.78 | TXNRD1 (0.46) | TXNRD1TXNRD3TXNRD2TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2103596-A1 | Process for the preparation of N-(phenylethyl) anilines salts and solvates thereof useful as serotonin 5-HT6 antagonists | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2009-09-23 | — | — | EP | disclosed |