Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.66 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.59 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.57 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | PRKCA | P17252 | 1/20 | 0.51 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13543649 | 0.91 | L3MBTL1 (0.54) | MAOBNR4A2 | |
| SCHEMBL28584628 | 0.89 | L3MBTL1 (0.52) | MAOBNR4A2 | |
| SCHEMBL13686681 | 0.86 | PRKCA (0.66) | MAOBNR4A2PARP10FFAR1PRKCA | |
| SCHEMBL10263162 | 0.83 | MAOB (0.71) | MAOBNR4A2PARP10APPMAOA | |
| SCHEMBL22386737 | 0.82 | MAOB (0.70) | MAOBNR4A2PARP10APPMAOA | |
| SCHEMBL27305897 | 0.82 | ELANE (0.52) | PRKCAPRKCD | |
| SCHEMBL22267266 | 0.81 | MAOB (0.44) | MAOBNR4A2PARP10APPMAOA | |
| SCHEMBL2087139 | 0.80 | MAOB (1.00) | MAOBNR4A2PARP10MAOAHRH3 | |
| SCHEMBL13522153 | 0.79 | MAOB (0.55) | MAOBNR4A2PARP10APPMAOA | |
| SCHEMBL3732071 | 0.79 | RAB9A (0.55) | FFAR1PRKCAPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592362-B2 | Substituted imidazoles | PFIZER LIMITED (GB) | 2009-09-22 | — | — | US | disclosed |