Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13688370 | 0.93 | ALDH1A1 (0.38) | SMN1; SMN2GAAELANEPOLBALDH1A1 | |
| SCHEMBL13688398 | 0.91 | — | — | |
| SCHEMBL13688369 | 0.89 | KMT2A (0.42) | KMT2ASMN1; SMN2TDP1MAPTELANE | |
| SCHEMBL13688354 | 0.88 | ALDH1A1 (0.43) | SMN1; SMN2GAAELANEPOLBALDH1A1 | |
| SCHEMBL14019720 | 0.87 | L3MBTL1 (0.48) | KMT2AHTTSMN1; SMN2TDP1MAPT | |
| SCHEMBL14019706 | 0.81 | NR3C1 (0.31) | — | |
| SCHEMBL14019715 | 0.79 | CYP19A1 (0.33) | MAPT | |
| SCHEMBL13688400 | 0.78 | KMT2A (0.32) | KMT2AATMGAAMAPTXBP1 | |
| SCHEMBL14019682 | 0.78 | HSD17B10 (0.30) | — | |
| SCHEMBL13688396 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7585901-B2 | Polymerizable bicyclic cyclopropane derivatives and their use for the preparation of dental materials | IVOCLAR VIVADENT AG (LI) | 2009-09-08 | — | — | US | disclosed |
| US-7585901-B2 | Polymerizable bicyclic cyclopropane derivatives and their use for the preparation of dental materials | IVOCLAR VIVADENT AG (LI) | 2009-09-08 | — | — | US | disclosed |
| US-20080261118-A1 | OPTICAL RECORDING COMPOSITION AND HOLOGRAPHIC RECORDING MEDIUM | FUJIFILM CORPORATION (JP) | 2008-10-23 | — | — | US | disclosed |
| US-20080261118-A1 | OPTICAL RECORDING COMPOSITION AND HOLOGRAPHIC RECORDING MEDIUM | FUJIFILM CORPORATION (JP) | 2008-10-23 | — | — | US | disclosed |
| US-7365222-B2 | 1,1-Disubstituted 2-vinylcyclopropanes; free radical polymerizable monomers | IVOCLAR VIVADENT AG (LI) | 2008-04-29 | — | — | US | disclosed |
| US-7365222-B2 | 1,1-Disubstituted 2-vinylcyclopropanes; free radical polymerizable monomers | IVOCLAR VIVADENT AG (LI) | 2008-04-29 | — | — | US | disclosed |
| US-20070232719-A1 | POLYMERIZABLE BICYCLIC CYCLOPROPANE DERIVATIVES AND THEIR USE FOR THE PREPARATION OF DENTAL MATERIALS | IVOCLAR VIVADENT AG (LI) | 2007-10-04 | — | — | US | disclosed |
| US-20070232719-A1 | POLYMERIZABLE BICYCLIC CYCLOPROPANE DERIVATIVES AND THEIR USE FOR THE PREPARATION OF DENTAL MATERIALS | IVOCLAR VIVADENT AG (LI) | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232719-A1 | POLYMERIZABLE BICYCLIC CYCLOPROPANE DERIVATIVES AND THEIR USE FOR THE PREPARATION OF DENTAL MATERIALS | CBR1, CYP8B1, OXER1 | KMT2A 4457/4885HTT 3107/4885SMN1; SMN2 3723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.