Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.66 |
| ▸ | CTSK | P43235 | 8/20 | 0.61 |
| ▸ | CTSS | P25774 | 5/20 | 0.55 |
| ▸ | CTSL | P07711 | 4/20 | 0.55 |
| ▸ | CTSB | P07858 | 2/20 | 0.55 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TACR1 | P25103 | 2/20 | 0.50 |
| ▸ | KYNU | Q16719 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11127997 | 1.00 | SYK (0.66) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL21340066 | 1.00 | SYK (0.66) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL14207360 | 0.90 | CTSK (0.63) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL4641124 | 0.89 | SYK (0.59) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL6320951 | 0.89 | SYK (0.59) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL19485480 | 0.89 | CTSK (0.62) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL9219338 | 0.89 | CTSK (0.62) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL2137432 | 0.89 | SYK (0.62) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL2137438 | 0.89 | SYK (0.62) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL2677162 | 0.89 | SYK (0.59) | SYKCTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106844-A1 | INHIBITORS OF P38 MAP KINASE | CHROMA THERAPEUTICS LTD. (GB) | 2009-09-03 | — | — | WO | disclosed |