SCHEMBL2677162

SCHEMBL2677162

CC(C)(C)OC(=O)[C@H](CO)NC(=O)OCc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SYK P43405 1/20 0.59
CTSK P43235 8/20 0.56
CTSS P25774 5/20 0.55
CTSL P07711 3/20 0.55
CTSB P07858 2/20 0.55
PSMB5 P28074 1/20 0.54
PPARA Q07869 1/20 0.53
ALDH1A1 P00352 1/20 0.51
ALOX15 P16050 1/20 0.51
TACR1 P25103 2/20 0.50
KYNU Q16719 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6320951 1.00 SYK (0.59) SYKCTSKCTSSCTSLCTSB
SCHEMBL4641124 1.00 SYK (0.59) SYKCTSKCTSSCTSLCTSB
SCHEMBL376154 0.90 SYK (0.57) SYKCTSKCTSSCTSLCTSB
SCHEMBL995705 0.90 SYK (0.57) SYKCTSKCTSSCTSLCTSB
SCHEMBL2619553 0.90 SYK (0.57) SYKCTSKCTSSCTSLCTSB
SCHEMBL1562695 0.89 PPARA (0.59) SYKCTSKCTSSCTSLCTSB
SCHEMBL7172323 0.89 PPARA (0.59) SYKCTSKCTSSCTSLCTSB
SCHEMBL19485480 0.89 CTSK (0.62) SYKCTSKCTSSCTSLCTSB
SCHEMBL21340066 0.89 SYK (0.66) SYKCTSKCTSSCTSLCTSB
SCHEMBL13688643 0.89 SYK (0.66) SYKCTSKCTSSCTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025151608-A1 CONNECTING UNITS FOR LIGAND-DRUG CONJUGATES AND METHODS OF MAKING AND USING THEREOF SYSTIMMUNE, INC. (US) 2025-07-17 WO disclosed
EP-4552498-A1 METHOD FOR PREVENTING INSECT DAMAGE TO PLANTS AJINOMOTO CO., INC. (JP) 2025-05-14 EP disclosed
US-12286455-B2 Anthelmintic depsipeptide compounds Boehringer Ingelheim Animal Health USA Inc. (US) 2025-04-29 US disclosed
US-20250127166-A1 METHOD FOR PREVENTING INSECT DAMAGE TO PLANTS AJINOMOTO CO., INC. (JP) 2025-04-24 US disclosed
CN-118255684-B CD4 enhancement+Compounds for T cell differentiation into Th9 cells 广州医科大学 2025-03-07 CN disclosed
CN-118255684-A CD4 enhancement+Compounds for T cell differentiation into Th9 cells 广州医科大学 2024-06-28 CN disclosed
WO-2024010005-A1 METHOD FOR PREVENTING INSECT DAMAGE TO PLANTS 味の素株式会社 2024-01-11 WO disclosed
US-11382949-B2 Anthelmintic depsipeptide compounds Boehringer Ingelheim Animal Health USA Inc. (US) 2022-07-12 US disclosed
US-11382949-B2 Anthelmintic depsipeptide compounds Boehringer Ingelheim Animal Health USA Inc. (US) 2022-07-12 US disclosed
US-10793604-B2 Anthelmintic depsipeptide compounds Boehringer Ingelheim Animal Health USA Inc. (US) 2020-10-06 US disclosed
EP-1210348-A1 NAPHTHYRIDINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM Aventis Pharma Deutschland GmbH (DE) 2002-06-05 EP disclosed
EP-1196416-A1 SUBSTITUTED PURINE DERIVATIVES AS INHIBITORS OF CELL ADHESION Aventis Pharma Deutschland GmbH (DE) 2002-04-17 EP disclosed
WO-2001002399-A1 SUBSTITUTED PURINE DERIVATIVES AS INHIBITORS OF CELL ADHESION AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2001-01-11 WO disclosed
WO-2001002398-A1 NAPHTHYRIDINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2001-01-11 WO disclosed
EP-1065208-A1 Substituted purine derivatives as inhibitors of cell adhesion Aventis Pharma Deutschland GmbH (DE) 2001-01-03 EP disclosed
EP-1065207-A1 Naphthyridine derivatives, processes for their preparation, their use, and pharmaceutical compositions comprising them Aventis Pharma Deutschland GmbH (DE) 2001-01-03 EP disclosed
CN-1193623-A Substituted purine derivatives, their preparation, their use and compositions containing them HOECHST AG (DE) 1998-09-23 CN disclosed
EP-0853084-A2 Substituted purine derivatives as vitronectin receptor antagonists HOECHST AKTIENGESELLSCHAFT (DE) 1998-07-15 EP disclosed
EP-0518675-A2 Cyclic renin inhibitors MERCK & CO. INC. (US) 1992-12-16 EP disclosed
EP-0431972-A2 Macrocyclic lactones having renin inhibiting properties MERCK & CO. INC. (US) 1991-06-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11382949-B2 Anthelmintic depsipeptide compounds ENPP2, ROCK2, RRP12 SYK 1165/4885CTSK 1247/4885CTSS 548/4885
US-20250127166-A1 METHOD FOR PREVENTING INSECT DAMAGE TO PLANTS GGT1, GGH, CAT SYK 4716/4885CTSK 886/4885CTSS 1745/4885
US-10793604-B2 Anthelmintic depsipeptide compounds VIP, PREP, DNPEP SYK 3404/4885CTSK 204/4885CTSS 245/4885
US-12286455-B2 Anthelmintic depsipeptide compounds VIP, PREP, DNPEP SYK 3404/4885CTSK 204/4885CTSS 245/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.