Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.59 |
| ▸ | CTSK | P43235 | 8/20 | 0.56 |
| ▸ | CTSS | P25774 | 5/20 | 0.55 |
| ▸ | CTSL | P07711 | 3/20 | 0.55 |
| ▸ | CTSB | P07858 | 2/20 | 0.55 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TACR1 | P25103 | 2/20 | 0.50 |
| ▸ | KYNU | Q16719 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6320951 | 1.00 | SYK (0.59) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL2677162 | 1.00 | SYK (0.59) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL376154 | 0.90 | SYK (0.57) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL995705 | 0.90 | SYK (0.57) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL2619553 | 0.90 | SYK (0.57) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL1562695 | 0.89 | PPARA (0.59) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL7172323 | 0.89 | PPARA (0.59) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL19485480 | 0.89 | CTSK (0.62) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL21340066 | 0.89 | SYK (0.66) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL13688643 | 0.89 | SYK (0.66) | SYKCTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853084-B1 | Substituted purine derivatives as vitronectin receptor antagonists | HOECHST AG (DE) | 2008-08-13 | — | — | EP | disclosed |
| EP-0839155-B1 | CYSTEINE PROTEASE INHIBITORS FOR USE IN TREATMENT OF IgE MEDIATED ALLERGIC DISEASES | MEDIVIR UK LTD (GB) | 2004-10-13 | — | — | EP | disclosed |
| CN-1495184-A | Substituted purine derivative, its preparation method, application and composition containing it | �ճ�˹�عɷݹ�˾ | 2004-05-12 | — | — | CN | disclosed |
| US-6723727-B1 | VITRONECTIN RECEPTOR ANTAGONISTS; INHIBITORS OF BONE RESORPTION; OSTEOPOROSIS | HOECHST AKTIENGESELLSCHAFT (DE) | 2004-04-20 | — | — | US | disclosed |
| CN-1101816-C | Substituted purine derivatives, their preparation, their use and compositions containing them | HOECHST AG (DE) | 2003-02-19 | — | — | CN | disclosed |
| US-6034066-A | ANTIALLERGENS | PEPTIDE THERAPEUTICS LIMITED (GB) | 2000-03-07 | — | — | US | disclosed |
| CN-1193623-A | Substituted purine derivatives, their preparation, their use and compositions containing them | HOECHST AG (DE) | 1998-09-23 | — | — | CN | disclosed |
| EP-0853084-A2 | Substituted purine derivatives as vitronectin receptor antagonists | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-15 | — | — | EP | disclosed |
| EP-0839155-A1 | CYSTEINE PROTEASE INHIBITORS FOR USE IN TREATMENT OF IgE MEDIATED ALLERGIC DISEASES | PEPTIDE THERAPEUTICS LIMITED (GB) | 1998-05-06 | — | — | EP | disclosed |
| WO-1997004004-A1 | CYSTEINE PROTEASE INHIBITORS FOR USE IN TREATMENT OF IgE MEDIATED ALLERGIC DISEASES | PEPTIDE THERAPEUTICS LIMITED (GB) | 1997-02-06 | — | — | WO | disclosed |