Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 3/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13689399 | 0.93 | LMNA (0.43) | LMNAPKMHTTKMT2AEGFR | |
| SCHEMBL13691674 | 0.90 | DRD2 (0.41) | LMNAPKMHTTKMT2AEGFR | |
| SCHEMBL13689400 | 0.89 | HDAC3 (0.44) | LMNAUTS2RPKMHTTKMT2A | |
| SCHEMBL13190967 | 0.86 | MAPT (0.47) | LMNAUTS2RPKMHTTKMT2A | |
| SCHEMBL13689395 | 0.83 | HDAC3 (0.35) | LMNAPKMHTTKMT2AEGFR | |
| SCHEMBL13689531 | 0.80 | DRD3 (0.52) | KMT2ASMN1; SMN2 | |
| SCHEMBL13689517 | 0.80 | GAA (0.38) | LMNAKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL13691792 | 0.79 | DRD2 (0.52) | KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL13190970 | 0.79 | DRD2 (0.51) | SMN1; SMN2 | |
| SCHEMBL13188820 | 0.78 | DRD2 (0.41) | LMNAPKMHTTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009105823-A1 | 3-AMINOALKYL-1,4-DIAZEPAN-2-ONE MELANOCORTIN-5 RECEPTOR ANTAGONISTS | MIMETICA PTY LTD (AU) | 2009-09-03 | — | — | WO | disclosed |
| WO-2009105824-A1 | METHODS OF MODULATING THE ACTIVITY OF THE MC5 RECEPTOR AND TREATMENT OF CONDITIONS RELATED TO THIS RECEPTOR | MIMETICA PTY LTD (AU) | 2009-09-03 | — | — | WO | disclosed |