Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SNCA | P37840 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 6/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13689519 | 0.90 | LMNA (0.48) | LMNAPKMHTTKMT2AESR1 | |
| SCHEMBL13689399 | 0.90 | LMNA (0.43) | LMNAPKMHTTKMT2AESR1 | |
| SCHEMBL13689400 | 0.86 | HDAC3 (0.44) | DRD2DRD3LMNAPKMHTT | |
| SCHEMBL13190967 | 0.84 | MAPT (0.47) | DRD2DRD3LMNAPKMHTT | |
| SCHEMBL13689395 | 0.80 | HDAC3 (0.35) | DRD2DRD3LMNAPKMHTT | |
| SCHEMBL13689531 | 0.77 | DRD3 (0.52) | DRD2DRD3KMT2A | |
| SCHEMBL13689517 | 0.77 | GAA (0.38) | DRD2DRD3LMNAKMT2AALDH1A1 | |
| SCHEMBL13691792 | 0.76 | DRD2 (0.52) | DRD2DRD3KMT2AMAPTCCR2 | |
| SCHEMBL13190970 | 0.76 | DRD2 (0.51) | DRD2DRD3MAPTCCR2 | |
| SCHEMBL13188820 | 0.75 | DRD2 (0.41) | DRD2DRD3LMNAPKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009105823-A1 | 3-AMINOALKYL-1,4-DIAZEPAN-2-ONE MELANOCORTIN-5 RECEPTOR ANTAGONISTS | MIMETICA PTY LTD (AU) | 2009-09-03 | — | — | WO | disclosed |