Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.51 |
| ▸ | TACR2 | P21452 | 2/20 | 0.48 |
| ▸ | SMYD2 | Q9NRG4 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13190976 | 0.95 | OPRK1 (0.52) | OPRK1TACR2SMYD2KDM4EALDH1A1 | |
| SCHEMBL13691863 | 0.92 | TACR2 (0.49) | OPRK1TACR2SMYD2KDM4EALDH1A1 | |
| SCHEMBL13689526 | 0.89 | SMYD2 (0.45) | SMYD2EPHX2DRD2DRD3 | |
| SCHEMBL13691797 | 0.89 | DRD2 (0.54) | TMEM97SIGMAR1DRD2DRD3DRD4 | |
| SCHEMBL13691800 | 0.87 | OPRK1 (0.49) | OPRK1TACR2KDM4EALDH1A1RAB9A | |
| SCHEMBL13691662 | 0.86 | TMEM97 (0.47) | OPRK1RAB9ATMEM97SIGMAR1EPHX2 | |
| SCHEMBL13691861 | 0.82 | OPRK1 (0.55) | OPRK1TACR2KDM4EALDH1A1RAB9A | |
| SCHEMBL13190970 | 0.79 | DRD2 (0.51) | DRD2DRD3CCR2 | |
| SCHEMBL13689531 | 0.79 | DRD3 (0.52) | DRD2DRD3 | |
| SCHEMBL13691792 | 0.78 | DRD2 (0.52) | DRD2DRD3CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009105824-A1 | METHODS OF MODULATING THE ACTIVITY OF THE MC5 RECEPTOR AND TREATMENT OF CONDITIONS RELATED TO THIS RECEPTOR | MIMETICA PTY LTD (AU) | 2009-09-03 | — | — | WO | disclosed |