Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.52 |
| ▸ | TACR2 | P21452 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.41 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.41 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13689521 | 0.95 | OPRK1 (0.51) | OPRK1TACR2RAB9AEPHX2KDM4E | |
| SCHEMBL13691863 | 0.87 | TACR2 (0.49) | OPRK1TACR2RAB9AKDM4EALDH1A1 | |
| SCHEMBL13689526 | 0.84 | SMYD2 (0.45) | EPHX2SMYD2CACNA1G | |
| SCHEMBL13691861 | 0.84 | OPRK1 (0.55) | OPRK1TACR2RAB9AKDM4EALDH1A1 | |
| SCHEMBL13691662 | 0.84 | TMEM97 (0.47) | OPRK1RAB9AEPHX2TMEM97SIGMAR1 | |
| SCHEMBL13691797 | 0.83 | DRD2 (0.54) | TMEM97SIGMAR1 | |
| SCHEMBL13691800 | 0.82 | OPRK1 (0.49) | OPRK1TACR2RAB9ACCR5KDM4E | |
| SCHEMBL13691855 | 0.82 | DRD2 (0.45) | OPRK1TACR2ALDH1A1UTS2RCACNA1G | |
| SCHEMBL13691857 | 0.81 | DRD2 (0.45) | OPRK1TACR2ALDH1A1UTS2R | |
| SCHEMBL13691854 | 0.81 | OPRK1 (0.47) | OPRK1TACR2RAB9AEPHX2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010096853-A1 | METHODS OF MODULATING THE ACTIVITY OF THE MC1 RECEPTOR AND TREATMENT OF CONDITIONS RELATED TO THIS RECEPTOR | MIMETICA PTY LTD (AU) | 2010-09-02 | — | — | WO | disclosed |