Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 9/20 | 0.61 |
| ▸ | CA1 | P00915 | 7/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17774980 | 0.83 | PTPN11 (0.67) | PTPN11PTPN1MAPK1SMN1; SMN2CA2 | |
| SCHEMBL10623902 | 0.81 | CA2 (0.66) | PTPN11PTPN1MAPK1SMN1; SMN2CA2 | |
| SCHEMBL7527132 | 0.81 | PTPN1 (0.66) | PTPN11PTPN1MAPK1SMN1; SMN2CA2 | |
| SCHEMBL7525890 | 0.80 | CA2 (0.68) | PTPN11PTPN1MAPK1SMN1; SMN2CA2 | |
| SCHEMBL7528321 | 0.80 | PTPN11 (0.79) | PTPN11PTPN1MAPK1SMN1; SMN2CA2 | |
| SCHEMBL3155581 | 0.79 | PTPN1 (0.63) | PTPN11PTPN1MAPK1SMN1; SMN2CA2 | |
| SCHEMBL4049597 | 0.79 | CA2 (0.67) | PTPN11PTPN1MAPK1SMN1; SMN2CA2 | |
| SCHEMBL7435640 | 0.79 | PTPN1 (0.63) | PTPN11PTPN1MAPK1SMN1; SMN2CA2 | |
| SCHEMBL11121097 | 0.79 | PTPN11 (0.72) | PTPN11PTPN1MAPK1SMN1; SMN2CA2 | |
| SCHEMBL7524156 | 0.79 | PTPN1 (0.63) | PTPN11PTPN1MAPK1SMN1; SMN2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |