Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.33 |
| ▸ | WDR5 | P61964 | 2/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL309183 | 0.74 | ENPP2 (0.46) | ENPP2PTGS2LMNA | |
| SCHEMBL2550551 | 0.69 | PTGS2 (0.39) | CA1CA2ENPP2PTGS2CA12 | |
| SCHEMBL2553579 | 0.69 | CA12 (0.44) | CA1CA2PTGS2ALDH1A1LMNA | |
| SCHEMBL309298 | 0.67 | SMN1; SMN2 (0.39) | PTGS2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10225172 | 0.67 | SMN1; SMN2 (0.32) | ENPP2SMN1; SMN2 | |
| SCHEMBL2556288 | 0.67 | ERN1 (0.31) | ENPP2PTGS2LMNA | |
| SCHEMBL16651363 | 0.66 | TTR (0.48) | CA1CA2ENPP2WDR5MEN1 | |
| SCHEMBL1334156 | 0.65 | ENPP2 (0.48) | CA1CA2ENPP2PTGS2LMNA | |
| SCHEMBL309246 | 0.64 | HTT (0.46) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL18184228 | 0.64 | TPMT (0.45) | ACP1CA1CA2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109483-A1 | LEUKOTRIENE B4 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-09-11 | — | — | WO | disclosed |