Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16962807 | 0.76 | PTGS2 (0.38) | PTGS2 | |
| SCHEMBL2264873 | 0.76 | PTGS2 (0.38) | PTGS2 | |
| SCHEMBL2555911 | 0.76 | ALDH1A1 (0.41) | ERN1PTGS2ENPP2 | |
| SCHEMBL16439841 | 0.75 | ERN1 (0.41) | ERN1PTGS2 | |
| SCHEMBL6897431 | 0.75 | ERN1 (0.41) | ERN1PTGS2 | |
| SCHEMBL19060103 | 0.73 | LOX (0.41) | LMNA | |
| SCHEMBL309183 | 0.71 | ENPP2 (0.46) | PTGS2ENPP2LMNA | |
| SCHEMBL17663615 | 0.70 | CYP2A6 (0.42) | ERN1 | |
| SCHEMBL41941 | 0.69 | CA12 (0.47) | — | |
| SCHEMBL30402657 | 0.69 | CA12 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011123937-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIVERSITY HEALTH NETWORK (CA) | 2011-10-13 | — | — | WO | disclosed |