Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126991 | 0.85 | AKR1B1 (0.61) | AKR1B1KDM4ENPC1RAB9ANR2F2 | |
| SCHEMBL1126796 | 0.81 | CNR2 (0.46) | AKR1B1KDM4ENPC1RAB9ANR2F2 | |
| SCHEMBL1126874 | 0.79 | CA12 (0.52) | KDM4ERAB9AALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL1126850 | 0.76 | SLC18A3 (0.45) | KDM4ENPC1RAB9ANR2F2CNR2 | |
| SCHEMBL5870352 | 0.76 | NTSR1 (0.40) | AKR1B1KDM4ENPC1RAB9ANR2F2 | |
| SCHEMBL10911282 | 0.75 | IDH1 (0.38) | AKR1B1KDM4ENPC1RAB9ANR2F2 | |
| SCHEMBL12605596 | 0.75 | ALDH1A1 (0.40) | KDM4ENPC1RAB9ANR2F2MAPT | |
| SCHEMBL1126872 | 0.72 | CA12 (0.41) | KDM4ENPC1RAB9ANR2F2ALDH1A1 | |
| Biphenyl SCHEMBL11131611 | 0.71 | SMN1; SMN2 (0.64) | KDM4ENPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL1127117 | 0.70 | KDM4E (0.39) | KDM4ENPC1RAB9ANR2F2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090240058-A1 | Activator for Peroxisome Proliferator-Activating Receptor Delta | NIPPON CHEMIPHAR CO., LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090240058-A1 | Activator for Peroxisome Proliferator-Activating Receptor Delta | PPARG, PPARA, PPARD | AKR1B1 1075/4885KDM4E 3267/4885NPC1 1565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.