SCHEMBL1126850

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13692017	0.76	AKR1B1 (0.45)	ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E
	SCHEMBL27739321	0.74	ALDH1A1 (0.50)	SLC18A3ALDH1A1SMN1; SMN2RAB9AKDM4E
	SCHEMBL1126926	0.74	SLC18A3 (0.43)	SLC18A3ALDH1A1SMN1; SMN2NPC1RAB9A
	SCHEMBL1126872	0.73	CA12 (0.41)	ALDH1A1NPC1RAB9AKDM4ENR2F2
	SCHEMBL1126874	0.73	CA12 (0.52)	ALDH1A1SMN1; SMN2RAB9ACYP1A2CYP2C9
	SCHEMBL10815654	0.73	ALDH1A1 (0.47)	SLC18A3ALDH1A1SMN1; SMN2RAB9ACNR2
	SCHEMBL1126796	0.72	CNR2 (0.46)	ALDH1A1SMN1; SMN2NPC1RAB9ACYP1A2
	SCHEMBL1126991	0.72	AKR1B1 (0.61)	ALDH1A1NPC1RAB9AKDM4EMAPT
	SCHEMBL10898797	0.71	SLC18A3 (0.43)	SLC18A3ALDH1A1SMN1; SMN2NPC1RAB9A
	SCHEMBL13587983	0.70	ESR1 (0.63)	SLC18A3SMN1; SMN2NPC1RAB9ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.