SCHEMBL1369255

SCHEMBL1369255

Cc1cc(C)c(I)cc1I

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.35
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31291547 0.89 TTR (0.33) TTR
SCHEMBL12803312 0.89 TTR (0.33) TTR
SCHEMBL2221187 0.89 CYP3A4 (0.40) TTRCYP3A4TSHRMAPK1
SCHEMBL1685558 0.88 TTR (0.37) TTRCYP3A4TSHRMAPK1
SCHEMBL18892550 0.79 TTR (0.32) TTR
SCHEMBL20152427 0.78 BCHE (0.33) CYP3A4TSHRMAPK1
SCHEMBL19931888 0.78 CD44 (0.46) CYP3A4
SCHEMBL10304843 0.78 TTR (0.33) TTR
SCHEMBL7871735 0.78 MAPT (0.42) TTRCYP3A4TSHRMAPK1
SCHEMBL22017382 0.76 TTR (0.30) TTRCYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11530357-B2 Liquid crystal alignment agent and liquid crystal panel SHARP KABUSHIKI KAISHA (JP) 2022-12-20 US disclosed
US-20220220308-A1 POLYAMIDE-IMIDE BLOCK COPOLYMERS, PREPARATION METHOD THEREOF AND POLYAMIDE-IMIDE FILM COMPRISING THE SAME LG CHEM, LTD. (KR) 2022-07-14 US disclosed
WO-2021215381-A1 METHOD FOR PRODUCING CARBOXYL GROUP-CONTAINING CROSSLINKED POLYMER OR SALT THEREOF 東亞合成株式会社 (JP) 2021-10-28 WO disclosed
WO-2021215380-A1 CARBOXYL GROUP-CONTAINING CROSSLINKED POLYMER OR SALT THEREOF, AND USE THEREOF 東亞合成株式会社 (JP) 2021-10-28 WO disclosed
US-11158810-B2 Polycyclic compound and organic light emitting device comprising same LG CHEM, LTD. 2021-10-26 US disclosed
US-11158810-B2 Polycyclic compound and organic light emitting device comprising same LG CHEM, LTD. 2021-10-26 US disclosed
US-11156873-B2 Alignment film, liquid crystal panel, and method for producing liquid crystal panel SHARP KABUSHIKI KAISHA (JP) 2021-10-26 US disclosed
US-11149204-B2 Liquid crystal alignment agent composition, method for preparing liquid crystal alignment film using same, and liquid crystal alignment film and liquid crystal display using same LG CHEM, LTD. (KR) 2021-10-19 US disclosed
US-11118113-B2 2021-09-14 US disclosed
CN-108349852-B Polycyclic compound and organic light emitting device including the same 株式会社LG化学 2021-02-26 CN disclosed
US-20110284827-A1 INDENOFLUORENEDIONE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2011-11-24 US disclosed
US-20110284827-A1 INDENOFLUORENEDIONE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2011-11-24 US disclosed
US-20110284827-A1 INDENOFLUORENEDIONE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2011-11-24 US disclosed
EP-2371812-A1 INDENOFLUORENEDIONE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT Idemitsu Kosan Co., Ltd. (JP) 2011-10-05 EP disclosed
EP-2371812-A1 INDENOFLUORENEDIONE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT Idemitsu Kosan Co., Ltd. (JP) 2011-10-05 EP disclosed
US-7514589-B2 Method for producing aromatic iodides NIPPOH CHEMICALS CO., LTD. (JP) 2009-04-07 US disclosed
US-7514589-B2 Method for producing aromatic iodides NIPPOH CHEMICALS CO., LTD. (JP) 2009-04-07 US disclosed
US-20080146853-A1 Method for Producing Aromatic Iodides NIPPOH CHEMICALS CO., LTD. (JP) 2008-06-19 US disclosed
US-20080146853-A1 Method for Producing Aromatic Iodides NIPPOH CHEMICALS CO., LTD. (JP) 2008-06-19 US disclosed
EP-1837324-A1 PROCESS FOR PRODUCING AROMATIC IODINE COMPOUND Nippoh Chemicals Co., Ltd (JP) 2007-09-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11158810-B2 Polycyclic compound and organic light emitting device comprising same CRY1, CYP1A1, CYP1B1 TTR 4330/4885CYP3A4 20/4885TSHR 4435/4885
US-20110284827-A1 INDENOFLUORENEDIONE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT HSD17B11, HSD17B2, HSD17B1 TTR 1443/4885CYP3A4 308/4885TSHR 4523/4885
US-20080146853-A1 Method for Producing Aromatic Iodides TYR, NISCH, TH TTR 982/4885CYP3A4 16/4885TSHR 33/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.