Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13693941 | 1.00 | SLC22A6 (0.46) | SLC22A6GRIK1GRIK2MAPTGABRR1 | |
| SCHEMBL6329384 | 0.90 | SLC22A6 (0.52) | SLC22A6GRIK1GRIK2MAPTGABRR1 | |
| SCHEMBL6329381 | 0.90 | SLC22A6 (0.52) | SLC22A6GRIK1GRIK2MAPTGABRR1 | |
| SCHEMBL8257920 | 0.78 | SLC22A6 (0.48) | SLC22A6MAPTGABRR1LMNAGPR84 | |
| SCHEMBL7909130 | 0.78 | SLC22A6 (0.48) | SLC22A6MAPTGABRR1LMNAGPR84 | |
| SCHEMBL6453593 | 0.78 | SLC22A6 (0.75) | SLC22A6MAPTGABRR1LMNAGPR84 | |
| SCHEMBL31250070 | 0.77 | SLC22A6 (0.52) | SLC22A6MAPTGABRR1LMNAGPR84 | |
| SCHEMBL9176364 | 0.74 | FFAR1 (0.62) | MAPTLMNAGPR84FFAR1FFAR4 | |
| SCHEMBL9176370 | 0.74 | FFAR1 (0.62) | MAPTLMNAGPR84FFAR1FFAR4 | |
| SCHEMBL4747079 | 0.73 | SLC22A6 (0.48) | SLC22A6MAPTGABRR1LMNAGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227602-A1 | COMPOSITIONS AND TREATMENTS FOR INHIBITING KINASE AND/OR HMG-COA REDUCTASE | NUMERATE, INC. | 2009-09-10 | — | — | US | disclosed |
| US-20080021054-A1 | COMPOSITIONS AND TREATMENTS FOR INHIBITING KINASE AND/OR HMG-COA REDUCTASE | NUMERATE, INC. | 2008-01-24 | — | — | US | disclosed |
| US-20070015779-A1 | COMPOSITIONS AND TREATMENTS FOR INHIBITING KINASE AND/OR HMG-COA REDUCTASE | NUMERATE, INC. | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227602-A1 | COMPOSITIONS AND TREATMENTS FOR INHIBITING KINASE AND/OR HMG-COA REDUCTASE | HMGCR, HMGB3, HMGB2 | SLC22A6 3429/4885GRIK1 686/4885GRIK2 903/4885 |
| US-20070015779-A1 | COMPOSITIONS AND TREATMENTS FOR INHIBITING KINASE AND/OR HMG-COA REDUCTASE | HMGCR, HMGB3, HMGB2 | SLC22A6 3387/4885GRIK1 682/4885GRIK2 890/4885 |
| US-20080021054-A1 | COMPOSITIONS AND TREATMENTS FOR INHIBITING KINASE AND/OR HMG-COA REDUCTASE | HMGCR, HMGB3, HMGB2 | SLC22A6 3386/4885GRIK1 682/4885GRIK2 893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.