Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.75 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.37 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6557026 | 0.89 | SLC22A6 (0.60) | SLC22A6GABRR1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL1135908 | 0.89 | SLC22A6 (0.60) | SLC22A6GABRR1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL4671010 | 0.89 | SLC22A6 (0.60) | SLC22A6GABRR1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL25427974 | 0.88 | SLC22A6 (0.67) | SLC22A6GABRR1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL15627218 | 0.87 | SLC22A6 (0.57) | SLC22A6GABRR1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL1135965 | 0.87 | SLC22A6 (0.57) | SLC22A6GABRR1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL8893405 | 0.87 | SLC22A6 (0.57) | SLC22A6GABRR1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL15627219 | 0.87 | SLC22A6 (0.57) | SLC22A6GABRR1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL17204173 | 0.87 | SLC22A6 (0.57) | SLC22A6GABRR1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL8893398 | 0.87 | SLC22A6 (0.57) | SLC22A6GABRR1LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295195-A1 | ANTIMICROBIAL ORGANOSILANES | Tipikos Pharmaceuticals, Inc. (US) | 2023-09-21 | — | — | US | disclosed |
| US-20230143708-A1 | ANTIMICROBIAL ORGANOSILANES | TOPIKOS PHARMACEUTICALS, INC. (US) | 2023-05-11 | — | — | US | disclosed |
| EP-1049784-B1 | POLYHYDROXYALKANOATE BIOSYNTHESIS-RELATED GENES DERIVED FROM ALCALIGENES LATUS | LG CHEMICAL LTD (KR) | 2005-04-20 | — | — | EP | disclosed |
| US-6649382-B1 | Culturing cell transformed with a expression vector comprising DNA fragment with three open reading frames; synthase, beta-ketothiolase and acetoacetyl-CoA reductase; biodegradable | LG CHEMICAL LTD. (KR) | 2003-11-18 | — | — | US | disclosed |
| EP-1049784-A1 | POLYHYDROXYALKANOATE BIOSYNTHESIS-RELATED GENES DERIVED FROM ALCALIGENES LATUS | LG CHEMICAL LTD. (KR) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999036547-A1 | POLYHYDROCYALKANOATE BIOSYNTHESIS-RELATED GENES DERIVED FROM $i(ALCALIGENES LATUS) | LG CHEMICAL LTD. (KR) | 1999-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230143708-A1 | ANTIMICROBIAL ORGANOSILANES | ARG1, ACMSD, AAAS | SLC22A6 1842/4885GABRR1 3637/4885LMNA 4596/4885 |
| US-20230295195-A1 | ANTIMICROBIAL ORGANOSILANES | ARG1, ACMSD, AAAS | SLC22A6 1842/4885GABRR1 3637/4885LMNA 4596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.