Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.54 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | MMP12 | P39900 | 2/20 | 0.43 |
| ▸ | MMP14 | P50281 | 2/20 | 0.43 |
| ▸ | GLP1R | P43220 | 8/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8171251 | 0.90 | NOD1 (0.60) | CASP2NOD1NAAAGLP1REPHX2 | |
| SCHEMBL18116882 | 0.87 | MEN1 (0.57) | CASP2NOD1FOLH1ALBEPHX2 | |
| SCHEMBL23452088 | 0.86 | NOD1 (0.61) | CASP2NOD1FOLH1ALBGLP1R | |
| SCHEMBL13057100 | 0.86 | NOD1 (0.61) | CASP2NOD1FOLH1ALBGLP1R | |
| SCHEMBL19401719 | 0.84 | CASP2 (0.54) | CASP2NOD1FOLH1NAAAALB | |
| SCHEMBL32679724 | 0.84 | NOD1 (0.60) | CASP2NOD1FOLH1ALBGLP1R | |
| SCHEMBL22449512 | 0.84 | CASP2 (0.54) | CASP2NOD1FOLH1NAAAALB | |
| SCHEMBL14586421 | 0.84 | CASP2 (0.54) | CASP2NOD1FOLH1NAAAALB | |
| SCHEMBL13694015 | 0.84 | NOD1 (0.47) | CASP2NOD1FOLH1ALBGLP1R | |
| SCHEMBL12674095 | 0.83 | EPHX2 (0.48) | NOD1FOLH1ALBGLP1REPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009115469-A1 | PROTEASE STABILIZED, ACYLATED INSULIN ANALOGUES | NOVO NORDISK A/S (DK) | 2009-09-24 | — | — | WO | disclosed |