Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.40 |
| ▸ | ALB | P02768 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CASP2 | P42575 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13694032 | 0.87 | CASP2 (0.54) | FOLH1NOD1ALBEPHX2CASP2 | |
| SCHEMBL13197601 | 0.85 | MEN1 (0.59) | MEN1KMT2AFOLH1NOD1ALB | |
| SCHEMBL14217259 | 0.85 | MEN1 (0.59) | MEN1KMT2AFOLH1NOD1ALB | |
| SCHEMBL16384378 | 0.85 | MEN1 (0.59) | MEN1KMT2AFOLH1NOD1ALB | |
| SCHEMBL16384384 | 0.85 | MEN1 (0.59) | MEN1KMT2AFOLH1NOD1ALB | |
| SCHEMBL8171251 | 0.83 | NOD1 (0.60) | NOD1EPHX2CASP2 | |
| SCHEMBL12919637 | 0.82 | MEN1 (0.55) | MEN1KMT2AFOLH1NOD1ALB | |
| SCHEMBL15871316 | 0.82 | ALB (0.56) | MEN1KMT2AFOLH1NOD1ALB | |
| SCHEMBL25548901 | 0.81 | MEN1 (0.53) | MEN1KMT2AFOLH1NOD1ALB | |
| SCHEMBL13694015 | 0.80 | NOD1 (0.47) | FOLH1NOD1ALBEPHX2CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2910570-B1 | Protease stabilized, acylated insulin analogues | NOVO NORDISK AS (DK) | 2016-10-12 | — | — | EP | disclosed |
| EP-2910569-B1 | Protease stabilized, acylated insulin analogues | NOVO NORDISK AS (DK) | 2016-10-05 | — | — | EP | disclosed |
| EP-2910571-B1 | PROTEASE STABILIZED, ACYLATED INSULIN ANALOGUES | NOVO NORDISK AS (DK) | 2016-10-05 | — | — | EP | disclosed |