Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.77 |
| ▸ | RAB9A | P51151 | 7/20 | 0.77 |
| ▸ | MAPT | P10636 | 7/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.77 |
| ▸ | LMNA | P02545 | 6/20 | 0.77 |
| ▸ | NPC1 | O15118 | 5/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.77 |
| ▸ | HTT | P42858 | 4/20 | 0.77 |
| ▸ | CDK2 | P24941 | 5/20 | 0.70 |
| ▸ | ATG4B | Q9Y4P1 | 3/20 | 0.70 |
| ▸ | GSK3A | P49840 | 1/20 | 0.70 |
| ▸ | GSK3B | P49841 | 1/20 | 0.70 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.70 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.70 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.70 |
| ▸ | CASP7 | P55210 | 2/20 | 0.65 |
| ▸ | CASP6 | P55212 | 2/20 | 0.65 |
| ▸ | ALPL | P05186 | 2/20 | 0.65 |
| ▸ | NSD2 | O96028 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3914581 | 0.88 | ATG4B (0.72) | MEN1KMT2ARAB9AMAPTALDH1A1 | |
| SCHEMBL18529266 | 0.87 | RAB9A (1.00) | MEN1KMT2ARAB9AMAPTALDH1A1 | |
| SCHEMBL1394449 | 0.86 | RAB9A (0.75) | MEN1KMT2ARAB9AMAPTALDH1A1 | |
| SCHEMBL29057112 | 0.85 | MEN1 (0.64) | MEN1KMT2ARAB9AMAPTALDH1A1 | |
| SCHEMBL27766071 | 0.85 | ATG4B (0.71) | MEN1KMT2ARAB9AMAPTALDH1A1 | |
| SCHEMBL5485450 | 0.84 | RAB9A (0.77) | MEN1KMT2ARAB9AMAPTALDH1A1 | |
| SCHEMBL13694243 | 0.84 | MEN1 (0.62) | MEN1KMT2ARAB9AMAPTALDH1A1 | |
| SCHEMBL1395185 | 0.83 | ATG4B (0.74) | MEN1KMT2ARAB9AMAPTALDH1A1 | |
| SCHEMBL7067199 | 0.82 | ALPL (0.85) | MEN1KMT2ARAB9AMAPTALDH1A1 | |
| SCHEMBL1394887 | 0.82 | ATG4B (1.00) | CDK2ATG4BGSK3AGSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221647-A1 | N-(2-THIAZOLYL)-AMIDE DERIVATIVES AS GSK-3 INHIBITORS | NOSCIRA, S.A. (ES) | 2009-09-03 | — | — | US | disclosed |
| US-20090221647-A1 | N-(2-THIAZOLYL)-AMIDE DERIVATIVES AS GSK-3 INHIBITORS | NOSCIRA, S.A. (ES) | 2009-09-03 | — | — | US | disclosed |
| WO-2007125110-A1 | N- ( 2-THIAZOLYL) -AMIDE DERIVATIVES AS GSK-3 INHIBITORS | NOSCIRA, S.A. (ES) | 2007-11-08 | — | — | WO | disclosed |
| EP-1849785-A1 | N-(2-Thiazolyl)-amide derivatives as GSK-3 inhibitors | Neuropharma, S.A. (ES) | 2007-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221647-A1 | N-(2-THIAZOLYL)-AMIDE DERIVATIVES AS GSK-3 INHIBITORS | GSK3B, GSK3A, GSKIP | MEN1 2935/4885KMT2A 1631/4885RAB9A 3781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.