Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GALR3 | O60755 | 1/20 | 0.49 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.49 |
| ▸ | GPR183 | P32249 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16901922 | 0.96 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNARAB9AMEN1KMT2A | |
| SCHEMBL18672266 | 0.95 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNARAB9AMEN1KMT2A | |
| SCHEMBL14768943 | 0.90 | NPC1 (0.52) | SMN1; SMN2LMNARAB9AMEN1KMT2A | |
| SCHEMBL18672249 | 0.90 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNARAB9AMEN1KMT2A | |
| SCHEMBL18672246 | 0.89 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNARAB9AMEN1KMT2A | |
| SCHEMBL14761331 | 0.89 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNARAB9AMEN1KMT2A | |
| SCHEMBL15596642 | 0.89 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNARAB9AMEN1KMT2A | |
| SCHEMBL9232300 | 0.89 | RAB9A (0.63) | SMN1; SMN2LMNARAB9AMEN1KMT2A | |
| SCHEMBL14760853 | 0.89 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNARAB9AMEN1KMT2A | |
| SCHEMBL9233810 | 0.88 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNARAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110984-A2 | CONTRAST AGENTS FOR APPLICATIONS INCLUDING PERFUSION IMAGING | LANTHEUS MEDICAL IMAGING, INC. (US) | 2009-09-11 | — | — | WO | disclosed |
| WO-2009108376-A2 | CONTRAST AGENTS FOR APPLICATIONS INCLUDING PERFUSION IMAGING | LANTHEUS MEDICAL IMAGING, INC. (US) | 2009-09-03 | — | — | WO | disclosed |