Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GALR3 | O60755 | 1/20 | 0.49 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.49 |
| ▸ | GPR183 | P32249 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18672266 | 0.95 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9ALMNAKMT2A | |
| SCHEMBL14768943 | 0.90 | NPC1 (0.52) | SMN1; SMN2NPC1RAB9ALMNAKMT2A | |
| SCHEMBL13694257 | 0.90 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9ALMNAKMT2A | |
| SCHEMBL18672246 | 0.89 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9ALMNAKMT2A | |
| SCHEMBL14760853 | 0.89 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9ALMNAKMT2A | |
| SCHEMBL9232300 | 0.89 | RAB9A (0.63) | SMN1; SMN2NPC1RAB9ALMNAKMT2A | |
| SCHEMBL14761331 | 0.89 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9ALMNAKMT2A | |
| SCHEMBL15596642 | 0.89 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9ALMNAKMT2A | |
| SCHEMBL9233810 | 0.88 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9ALMNAKMT2A | |
| SCHEMBL20159053 | 0.88 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9ALMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210187131-A1 | METHODS AND APPARATUS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF | LANTHEUS MEDICAL IMAGING, INC. (US) | 2021-06-24 | — | — | US | disclosed |
| US-10842892-B2 | Methods and apparatus for synthesizing imaging agents, and intermediates thereof | LANTHEUS MEDICAL IMAGING, INC. (US) | 2020-11-24 | — | — | US | disclosed |
| US-20190290788-A1 | METHODS AND APPARATUS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF | LANTHEUS MEDICAL IMAGING, INC. (US) | 2019-09-26 | — | — | US | disclosed |
| US-10022462-B2 | Methods and apparatus for synthesizing imaging agents, and intermediates thereof | LANTHEUS MEDICAL IMAGING, INC. (US) | 2018-07-17 | — | — | US | disclosed |
| EP-3323810-A2 | AUTOMATED REACTION SYSTEM, CASSETTE AND APPARATUS FOR SYNTHESIZING IMAGING AGENTS | Lantheus Medical Imaging, Inc. (US) | 2018-05-23 | — | — | EP | disclosed |
| US-20170258947-A1 | METHODS AND APPARATUS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF | LANTHEUS MEDICAL IMAGING, INC. (US) | 2017-09-14 | — | — | US | disclosed |
| EP-2534136-B1 | METHODS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF | LANTHEUS MEDICAL IMAGING INC (US) | 2017-09-06 | — | — | EP | disclosed |
| US-9603951-B2 | Methods and apparatus for synthesizing imaging agents, and intermediates thereof | LANTHEUS MEDICAL IMAGING, INC. (US) | 2017-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190290788-A1 | METHODS AND APPARATUS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF | TNNI3, FABP3, MPI | SMN1; SMN2 2628/4885NPC1 1259/4885RAB9A 3623/4885 |
| US-20210187131-A1 | METHODS AND APPARATUS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF | TNNI3, FABP3, MPI | SMN1; SMN2 2628/4885NPC1 1259/4885RAB9A 3623/4885 |
| US-10022462-B2 | Methods and apparatus for synthesizing imaging agents, and intermediates thereof | TNNI3, FABP3, MPI | SMN1; SMN2 2628/4885NPC1 1259/4885RAB9A 3623/4885 |
| US-10842892-B2 | Methods and apparatus for synthesizing imaging agents, and intermediates thereof | TNNI3, FABP3, MPI | SMN1; SMN2 2628/4885NPC1 1259/4885RAB9A 3623/4885 |
| US-20170258947-A1 | METHODS AND APPARATUS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF | TNNI3, FABP3, MPI | SMN1; SMN2 2628/4885NPC1 1259/4885RAB9A 3623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.