Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 5/20 | 0.35 |
| ▸ | CA2 | P00918 | 5/20 | 0.35 |
| ▸ | CA9 | Q16790 | 5/20 | 0.35 |
| ▸ | CA12 | O43570 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16509797 | 1.00 | LMNA (0.49) | LMNAKMT2AALDH1A1POLBKDM4E | |
| SCHEMBL13694947 | 0.87 | LMNA (0.57) | LMNAKMT2AALDH1A1POLBKDM4E | |
| SCHEMBL16509798 | 0.87 | LMNA (0.57) | LMNAKMT2AALDH1A1POLBKDM4E | |
| SCHEMBL17287141 | 0.83 | LMNA (0.51) | LMNAKMT2AALDH1A1POLBKDM4E | |
| SCHEMBL17287140 | 0.83 | LMNA (0.51) | LMNAKMT2AALDH1A1POLBKDM4E | |
| SCHEMBL23077722 | 0.83 | LMNA (0.51) | LMNAKMT2AALDH1A1POLBKDM4E | |
| SCHEMBL1737712 | 0.81 | LMNA (0.53) | LMNAKMT2AALDH1A1POLBKDM4E | |
| SCHEMBL15910280 | 0.81 | LMNA (0.53) | LMNAKMT2AALDH1A1POLBKDM4E | |
| SCHEMBL14031247 | 0.81 | LMNA (0.56) | LMNAKMT2AALDH1A1POLBKDM4E | |
| SCHEMBL14049596 | 0.81 | LMNA (0.56) | LMNAKMT2AALDH1A1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8076299-B2 | Method for producing peptide thioester | RIKEN (JP) | 2011-12-13 | — | — | US | disclosed |
| US-20090240034-A1 | METHOD FOR PRODUCING PEPTIDE THIOESTER | RIKEN (JP) | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090240034-A1 | METHOD FOR PRODUCING PEPTIDE THIOESTER | PTMS, PPT1, NGLY1 | LMNA 4397/4885KMT2A 1579/4885ALDH1A1 4214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.