Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GART | P22102 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL428455 | 0.82 | HCAR3 (0.53) | GARTLMNAALDH1A1MAPTKAT2B | |
| SCHEMBL10771350 | 0.79 | TDP1 (0.42) | GARTLMNAALDH1A1MAPTPOLB | |
| SCHEMBL3633359 | 0.79 | HCAR3 (0.55) | GARTLMNAALDH1A1MAPTPOLB | |
| SCHEMBL15384088 | 0.76 | LMNA (0.44) | GARTLMNAALDH1A1MAPTPOLB | |
| SCHEMBL10763236 | 0.76 | ATM (0.42) | GARTLMNAALDH1A1MAPTPOLB | |
| SCHEMBL6870232 | 0.76 | HCAR3 (0.49) | GARTLMNAALDH1A1MAPTPOLB | |
| SCHEMBL12210248 | 0.73 | LMNA (0.56) | GARTLMNAALDH1A1MAPTPOLB | |
| SCHEMBL3756498 | 0.73 | TDP1 (0.56) | LMNAALDH1A1MAPTPOLBNPSR1 | |
| SCHEMBL30257990 | 0.73 | TDP1 (0.56) | LMNAALDH1A1MAPTPOLBNPSR1 | |
| SCHEMBL18784835 | 0.72 | LMNA (0.44) | GARTLMNAALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109258-A1 | QUINOXALINONE DERIVATIVES AS INSULIN SECRETION STIMULATORS, METHODS FOR OBTAINING THEM AND USE THEREOF FOR THE TREATMENT OF DIABETES | MERCK PATENT GMBH (DE) | 2009-09-11 | — | — | WO | disclosed |