Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.54 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30257990 | 1.00 | TDP1 (0.56) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL58080 | 0.89 | TDP1 (0.58) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL29403879 | 0.89 | TDP1 (0.58) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL4670199 | 0.88 | TDP1 (0.62) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL28871017 | 0.86 | TDP1 (0.50) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| Benzene SCHEMBL28328708 | 0.85 | TDP1 (0.54) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL2477068 | 0.83 | TSHR (0.52) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL518140 | 0.83 | GPR35 (0.50) | TDP1ATMALDH1A1HIF1AMAPT | |
| SCHEMBL9220043 | 0.83 | TDP1 (0.47) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL199359 | 0.83 | MAPT (0.52) | TDP1ATMALDH1A1HIF1AVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307562-A | Triplex wall molecule calix macrocyclic host compound based on ramification of ralston calix [4] arene, and preparation method and application thereof | 上海大学 | 2024-07-09 | — | — | CN | claimed |
| CN-111269126-B | Preparation method of fusion casting carrier 1,2-difluoro-4,5-dinitrobenzene | 北京理工大学重庆创新中心 | 2023-04-07 | — | — | CN | claimed |
| CN-111302946-B | Recrystallization method of 1,2-difluoro-4,5-dinitrobenzene | 北京理工大学重庆创新中心 | 2023-03-24 | — | — | CN | claimed |
| CN-111302946-A | Recrystallization method of 1, 2-difluoro-4, 5-dinitrobenzene | 北京理工大学重庆创新中心 | 2020-06-19 | — | — | CN | claimed |
| CN-111269126-A | Preparation method of fusion-cast carrier 1, 2-difluoro-4, 5-dinitrobenzene | 北京理工大学重庆创新中心 | 2020-06-12 | — | — | CN | claimed |
| US-4970145-A | CARBON OR GRAPHITE PARTICLES IN RESIN | CAMBRIDGE LIFE SCIENCES PLC (GB) | 1990-11-13 | — | — | US | claimed |
| US-20250377357-A1 | SELF-ACTUATING SIGNAL PRODUCING DETECTION DEVICES AND METHODS | RED IVORY LLC (US) | 2025-12-11 | — | — | US | disclosed |
| EP-4466258-A1 | NEW BENZIMIDAZOLE PYRIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2024-11-27 | — | — | EP | disclosed |
| CN-118307562-A | Triplex wall molecule calix macrocyclic host compound based on ramification of ralston calix [4] arene, and preparation method and application thereof | 上海大学 | 2024-07-09 | — | — | CN | disclosed |
| US-12030877-B2 | Prostaglandin E synthase inhibitors and methods for utilizing the same | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2024-07-09 | — | — | US | disclosed |
| WO-2023139085-A1 | NEW BENZIMIDAZOLE PYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2023-07-27 | — | — | WO | disclosed |
| CN-116239605-A | Chiral organic photosensitive semiconductor and preparation method and application thereof | 华南理工大学 | 2023-06-09 | — | — | CN | disclosed |
| CN-111269126-B | Preparation method of fusion casting carrier 1,2-difluoro-4,5-dinitrobenzene | 北京理工大学重庆创新中心 | 2023-04-07 | — | — | CN | disclosed |
| US-5160418-A | ENZYME ELECTRODES AND IMPROVEMENTS IN THE MANUFACTURE THEREOF | CAMBRIDGE LIFE SCIENCES PLC (GB) | 1992-11-03 | — | — | US | disclosed |
| US-4970145-A | CARBON OR GRAPHITE PARTICLES IN RESIN | CAMBRIDGE LIFE SCIENCES PLC (GB) | 1990-11-13 | — | — | US | disclosed |
| EP-0352925-A2 | Enzyme electrodes and improvements in the manufacture thereof | CAMBRIDGE LIFE SCIENCES PLC (GB) | 1990-01-31 | — | — | EP | disclosed |
| EP-0343203-A1 | IMMOBILISED ENZYME ELECTRODES AND A METHOD FOR REDUCING THE ALCOHOL SENSITIVITY | CAMBRIDGE LIFE SCIENCES PLC (GB) | 1989-11-29 | — | — | EP | disclosed |
| WO-1989003871-A1 | IMMOBILISED ENZYME ELECTRODES AND A METHOD FOR REDUCING THE ALCOHOL SENSITIVITY | CAMBRIDGE LIFE SCIENCES PLC (GB) | 1989-05-05 | — | — | WO | disclosed |
| WO-1987007295-A1 | IMMOBILISED ENZYME ELECTRODES | CAMBRIDGE LIFE SCIENCES PLC (GB) | 1987-12-03 | — | — | WO | disclosed |
| EP-0247850-A1 | Immobilized enzyme electrodes | CAMBRIDGE LIFE SCIENCES PLC (GB) | 1987-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12030877-B2 | Prostaglandin E synthase inhibitors and methods for utilizing the same | PTGES, PTGS1, PTGES2 | TDP1 2276/4885ATM 4109/4885ALDH1A1 474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.