Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PMM2 | O15305 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29796039 | 0.93 | ALDH1A1 (0.53) | ALDH1A1CYP3A4TDP1HPGDGLA | |
| SCHEMBL23214234 | 0.93 | ALDH1A1 (0.53) | ALDH1A1CYP3A4TDP1HPGDGLA | |
| SCHEMBL6371043 | 0.86 | ALDH1A1 (0.49) | ALDH1A1CYP3A4TDP1HPGDGLA | |
| SCHEMBL3993039 | 0.86 | ALDH1A1 (0.56) | ALDH1A1CYP3A4TDP1HPGDTSHR | |
| SCHEMBL9825110 | 0.84 | CYP3A4 (0.58) | ALDH1A1CYP3A4TDP1HPGDTRPA1 | |
| SCHEMBL6372027 | 0.84 | CYP3A4 (0.58) | ALDH1A1CYP3A4TDP1HPGDTSHR | |
| SCHEMBL7159670 | 0.82 | ALDH1A1 (0.56) | ALDH1A1CYP3A4TDP1HPGDTRPA1 | |
| SCHEMBL1457541 | 0.82 | ALDH1A1 (0.56) | ALDH1A1CYP3A4TDP1HPGDTRPA1 | |
| SCHEMBL542663 | 0.81 | CYP3A4 (0.68) | ALDH1A1CYP3A4TDP1HPGDTSHR | |
| SCHEMBL668344 | 0.81 | ALDH1A1 (0.54) | ALDH1A1CYP3A4TDP1HPGDTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090234117-A1 | Pyrazolopyrimidine Derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090234117-A1 | Pyrazolopyrimidine Derivative | MC2R, CRHR1, AVPR2 | ALDH1A1 1328/4885CYP3A4 372/4885TDP1 3304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.