SCHEMBL1369652

SCHEMBL1369652

CC(=O)OC[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](F)C=O

nearest known ligand 0.71

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.71
POLB P06746 1/20 0.42
MAPK1 P28482 1/20 0.42
ABCB1 P08183 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL270042 0.86 TDP1 (0.96) TDP1POLBMAPK1ABCB1
SCHEMBL7152317 0.86 TDP1 (0.96) TDP1POLBMAPK1ABCB1
SCHEMBL13168216 0.86 TDP1 (0.96) TDP1POLBMAPK1ABCB1
SCHEMBL2175855 0.86 TDP1 (0.96) TDP1POLBMAPK1ABCB1
SCHEMBL7149374 0.86 TDP1 (0.96) TDP1POLBMAPK1ABCB1
SCHEMBL826717 0.86 TDP1 (0.96) TDP1POLBMAPK1ABCB1
SCHEMBL7150717 0.86 TDP1 (0.96) TDP1POLBMAPK1ABCB1
SCHEMBL2956079 0.84 TDP1 (1.00) TDP1POLBMAPK1ABCB1
SCHEMBL2956081 0.84 TDP1 (1.00) TDP1POLBMAPK1ABCB1
SCHEMBL18860460 0.83 TDP1 (0.71) TDP1POLBMAPK1ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0641350-A4 METHOD FOR MAKING 2-FLUORO-2-DEOXYGLUCOSE. GEN ELECTRIC (US) 1995-08-23 EP claimed
US-5436325-A Ion exchanging fluoride ion from resin and alkali metal bicarbonate, heating and treating with hydrogen halide GENERAL ELECTRIC COMPANY (US) 1995-07-25 US claimed
EP-0641350-A1 METHOD FOR MAKING 2-FLUORO-2-DEOXYGLUCOSE GENERAL ELECTRIC COMPANY (US) 1995-03-08 EP claimed
WO-1994021653-A1 METHOD FOR MAKING 2-FLUORO-2-DEOXYGLUCOSE GENERAL ELECTRIC COMPANY (US) 1994-09-29 WO claimed
US-20110288287-A1 Halogen Substituted Saccharide, Method for Producing Same, Reaction Composition of Same and Device for Producing Same NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2011-11-24 US disclosed
EP-2386562-A1 HALOGEN-SUBSTITUTED SACCHARIDE, METHOD FOR PRODUCING SAME, REACTION COMPOSITION OF SAME AND DEVICE FOR PRODUCING SAME National Institute of Advanced Industrial Science And Technology (JP) 2011-11-16 EP disclosed
US-8039752-B2 Heat dissipation structure of a print circuit board KEIHIN CORPORATION (JP) 2011-10-18 US disclosed
EP-0798307-B1 Fluoro-deoxyglucose synthesizer using columns NKK PLANT ENG CORP (JP) 2003-03-19 EP disclosed
EP-1134228-B1 Fluoro-deoxyglucose synthesizer using columns NKK PLANT ENG CORP (JP) 2003-03-05 EP disclosed
EP-0641350-A4 METHOD FOR MAKING 2-FLUORO-2-DEOXYGLUCOSE. GEN ELECTRIC (US) 1995-08-23 EP disclosed
EP-0641350-A4 METHOD FOR MAKING 2-FLUORO-2-DEOXYGLUCOSE. GEN ELECTRIC (US) 1995-08-23 EP disclosed
US-5436325-A Ion exchanging fluoride ion from resin and alkali metal bicarbonate, heating and treating with hydrogen halide GENERAL ELECTRIC COMPANY (US) 1995-07-25 US disclosed
US-5436325-A Ion exchanging fluoride ion from resin and alkali metal bicarbonate, heating and treating with hydrogen halide GENERAL ELECTRIC COMPANY (US) 1995-07-25 US disclosed
EP-0641350-A1 METHOD FOR MAKING 2-FLUORO-2-DEOXYGLUCOSE GENERAL ELECTRIC COMPANY (US) 1995-03-08 EP disclosed
EP-0641350-A1 METHOD FOR MAKING 2-FLUORO-2-DEOXYGLUCOSE GENERAL ELECTRIC COMPANY (US) 1995-03-08 EP disclosed
WO-1994021653-A1 METHOD FOR MAKING 2-FLUORO-2-DEOXYGLUCOSE GENERAL ELECTRIC COMPANY (US) 1994-09-29 WO disclosed
WO-1994021653-A1 METHOD FOR MAKING 2-FLUORO-2-DEOXYGLUCOSE GENERAL ELECTRIC COMPANY (US) 1994-09-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110288287-A1 Halogen Substituted Saccharide, Method for Producing Same, Reaction Composition of Same and Device for Producing Same FTO, SETD7, SETD2 TDP1 3341/4885POLB 2410/4885MAPK1 3327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.