Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.50 |
| ▸ | AGXT | P21549 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 5/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017219 | 0.88 | TSHR (0.43) | AGXTALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL8049409 | 0.81 | IDO1 (0.53) | IDO1AGXTALDH1A1HTTMAPT | |
| SCHEMBL25416123 | 0.81 | RAB9A (0.47) | AGXTALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL3765408 | 0.81 | TSHR (0.50) | IDO1AGXTALDH1A1HTTMAPT | |
| SCHEMBL5521298 | 0.80 | IDO1 (0.48) | IDO1AGXTALDH1A1HTTMAPT | |
| SCHEMBL5335331 | 0.79 | TSHR (0.60) | IDO1AGXTALDH1A1HTTMAPT | |
| SCHEMBL20840419 | 0.79 | IDO1 (0.57) | IDO1AGXTALDH1A1HTTMAPT | |
| SCHEMBL8389200 | 0.79 | NPC1 (0.53) | IDO1AGXTALDH1A1HTTMAPT | |
| SCHEMBL27595468 | 0.79 | IDO1 (0.57) | IDO1AGXTALDH1A1HTTMAPT | |
| SCHEMBL7110551 | 0.79 | IDO1 (0.45) | IDO1ALDH1A1MAPTPOLBAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110286777-A1 | LUBRICANT AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING SAME | RICOH COMPANY, LTD. (JP) | 2011-11-24 | — | — | US | disclosed |
| CN-1620294-A | Pyrimidine A2BSelective antagonist compounds, their synthesis and use | OSI PHARM INC (US) | 2005-05-25 | — | — | CN | disclosed |