Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 4/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | AGXT | P21549 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25416123 | 0.92 | RAB9A (0.47) | TSHRALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL28771589 | 0.90 | CYP3A4 (0.39) | TSHRCETPAKR1C3ALDH1A1RAB9A | |
| SCHEMBL28120336 | 0.90 | IDO1 (0.45) | ALDH1A1NPC1RAB9ALMNAMAPT | |
| SCHEMBL27889638 | 0.90 | CYP3A4 (0.45) | TSHRRXRARXRB | |
| SCHEMBL7110551 | 0.90 | IDO1 (0.45) | TSHRALDH1A1RXRARXRBMAPT | |
| SCHEMBL1369690 | 0.88 | IDO1 (0.50) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL27977375 | 0.87 | KMT2A (0.52) | ALDH1A1RAB9ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL27841628 | 0.84 | AKR1C3 (0.66) | TSHRAKR1C3ALDH1A1NPC1RAB9A | |
| SCHEMBL28804369 | 0.78 | ALDH1A1 (0.46) | ALDH1A1NPC1RAB9ALMNAMAPT | |
| SCHEMBL5809008 | 0.76 | EPHX2 (0.51) | ALDH1A1NPC1RAB9ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486441-A | CHARGE TRANSPORT | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1996-01-23 | — | — | US | disclosed |