Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 4/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13697100 | 0.88 | CYP19A1 (0.47) | CYP19A1CYP11B2ESR1PTGS2TDP1 | |
| SCHEMBL4827188 | 0.88 | TRIM24 (0.42) | CYP19A1CYP11B2ESR1TRIM24TRIM33 | |
| SCHEMBL4828680 | 0.86 | TRIM24 (0.43) | CYP19A1CYP11B2ESR1TRIM24TRIM33 | |
| SCHEMBL1102929 | 0.81 | CYP19A1 (0.51) | CYP19A1CYP11B2ESR1TDP1CYP2D6 | |
| SCHEMBL1103124 | 0.80 | CYP19A1 (0.43) | CYP19A1CYP11B2ESR1TDP1ESR2 | |
| SCHEMBL1103494 | 0.79 | ALDH1A1 (0.41) | CYP19A1CYP11B2ESR1TDP1ALDH1A1 | |
| SCHEMBL2086861 | 0.79 | CYP19A1 (0.44) | CYP19A1CYP11B2ESR1TRIM24TRIM33 | |
| SCHEMBL2322371 | 0.78 | ESR1 (0.58) | CYP19A1CYP11B2ESR1PTGS2ALDH1A1 | |
| SCHEMBL14510113 | 0.77 | KDM4E (0.38) | CYP19A1CYP11B2ESR1TDP1ALDH1A1 | |
| SCHEMBL4828677 | 0.77 | ESR1 (0.37) | CYP19A1CYP11B2ESR1TRIM24TRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090236975-A1 | SILICON-CONTAINING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE UTILIZING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090236975-A1 | SILICON-CONTAINING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE UTILIZING THE SAME | ESPL1, EML4, EED | CYP19A1 1484/4885CYP11B2 4103/4885ESR1 102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.