Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2356139 | 0.94 | MEN1 (0.36) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL10026448 | 0.92 | KDR (0.33) | MEN1KMT2ARAPGEF4MAPTALDH1A1 | |
| SCHEMBL1869939 | 0.91 | RAB9A (0.36) | MEN1KMT2ARAPGEF4MAPTALDH1A1 | |
| SCHEMBL2848598 | 0.88 | ESR1 (0.37) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL2349573 | 0.88 | KMT2A (0.38) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL14962991 | 0.88 | MAOB (0.40) | MEN1KMT2AMAPTALDH1A1CYP1A2 | |
| SCHEMBL69222 | 0.86 | NPC1 (0.44) | MEN1KMT2AHSD17B10IKBKBMAP3K14 | |
| SCHEMBL29369509 | 0.86 | NPC1 (0.44) | MEN1KMT2AHSD17B10IKBKBMAP3K14 | |
| SCHEMBL2354029 | 0.86 | MEN1 (0.43) | MEN1KMT2AMAPTHSD17B10CYP1A2 | |
| SCHEMBL1873945 | 0.85 | KMT2A (0.34) | MEN1KMT2ARAPGEF4MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221588-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION, INC. (US) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221588-A1 | FUNGICIDAL COMPOSITIONS | TUBB2B, TUBB, TUBB4B | MEN1 1901/4885KMT2A 1881/4885RAPGEF4 4293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.