Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.75 |
| ▸ | POLA1 | P09884 | 1/20 | 0.74 |
| ▸ | OSBP | P22059 | 4/20 | 0.70 |
| ▸ | RORC | P51449 | 3/20 | 0.70 |
| ▸ | USP2 | O75604 | 2/20 | 0.70 |
| ▸ | OSBP2 | Q969R2 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.70 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.62 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.60 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.60 |
| ▸ | GBA1 | P04062 | 2/20 | 0.59 |
| ▸ | UGCG | Q16739 | 2/20 | 0.59 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.59 |
| ▸ | NPC1L1 | Q9UHC9 | 4/20 | 0.59 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.58 |
| ▸ | CRYAB | P02511 | 1/20 | 0.57 |
| ▸ | HMGCR | P04035 | 1/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.57 |
| ▸ | ITGAV | P06756 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13523734 | 1.00 | CYP46A1 (0.75) | CYP46A1POLA1OSBPRORCUSP2 | |
| SCHEMBL7989828 | 1.00 | CYP46A1 (0.75) | CYP46A1POLA1OSBPRORCUSP2 | |
| SCHEMBL15605473 | 1.00 | CYP46A1 (0.75) | CYP46A1POLA1OSBPRORCUSP2 | |
| SCHEMBL18627850 | 1.00 | CYP46A1 (0.75) | CYP46A1POLA1OSBPRORCUSP2 | |
| SCHEMBL1045464 | 1.00 | CYP46A1 (0.75) | CYP46A1POLA1OSBPRORCUSP2 | |
| SCHEMBL13758209 | 1.00 | CYP46A1 (0.75) | CYP46A1POLA1OSBPRORCUSP2 | |
| SCHEMBL19460299 | 1.00 | CYP46A1 (0.75) | CYP46A1POLA1OSBPRORCUSP2 | |
| SCHEMBL22523945 | 1.00 | CYP46A1 (0.75) | CYP46A1POLA1OSBPRORCUSP2 | |
| SCHEMBL21935259 | 1.00 | CYP46A1 (0.75) | CYP46A1POLA1OSBPRORCUSP2 | |
| SCHEMBL13072641 | 1.00 | CYP46A1 (0.75) | CYP46A1POLA1OSBPRORCUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116847888-A | Composition for reducing hair whitening, promoting hair growth and/or preventing or reducing hair loss comprising double-stranded miRNA as active ingredient | 柏业公司 | 2023-10-03 | — | — | CN | claimed |
| EP-4229639-A1 | METHOD AND SYSTEMS FOR PHYTOMEDICINE ANALYTICS FOR RESEARCH OPTIMIZATION AT SCALE | GBS Global Biopharma, Inc. (CA) | 2023-08-23 | — | — | EP | claimed |
| CN-116157521-A | Double-stranded oligonucleotides and compositions containing same for the treatment of covd-19 | 柏业公司 | 2023-05-23 | — | — | CN | claimed |
| CN-114981433-A | CTGF gene-specific double-stranded oligonucleotides and compositions comprising the same for preventing and treating fibrotic diseases and respiratory-related diseases | 柏业公司 | 2022-08-30 | — | — | CN | claimed |
| EP-4025660-A1 | THERMOCHROMIC LIQUID CRYSTAL INKS AND COATINGS | Sun Chemical Corporation (US) | 2022-07-13 | — | — | EP | claimed |
| WO-2022081889-A1 | METHOD AND SYSTEMS FOR PHYTOMEDICINE ANALYTICS FOR RESEARCH OPTIMIZATION AT SCALE | GBS GLOBAL BIOPHARMA, INC. (CA) | 2022-04-21 | — | — | WO | claimed |
| US-11219692-B2 | Porphyrin modified telodendrimers | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-01-11 | — | — | US | claimed |
| CN-107652438-B | Drug delivery enhanced terminal dendrimers | 加利福尼亚大学董事会 | 2021-10-12 | — | — | CN | claimed |
| WO-2021046004-A1 | THERMOCHROMIC LIQUID CRYSTAL INKS AND COATINGS | SUN CHEMICAL CORPORATION (US) | 2021-03-11 | — | — | WO | claimed |
| CN-112159807-A | Novel double-stranded oligo-RNA and pharmaceutical composition for preventing or treating fibrosis or respiratory disease comprising the same | 柏业公司 | 2021-01-01 | — | — | CN | claimed |
| US-20150045419-A1 | REVERSIBLY CROSSLINKED MICELLE SYSTEMS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-02-12 | — | — | US | claimed |
| US-20140363371-A1 | TELODENDRIMERS WITH ENHANCED DRUG DELIVERY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2014-12-11 | — | — | US | claimed |
| US-8895055-B2 | Telodendrimer nanodiscs without apolipoprotein | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-11-25 | — | — | US | claimed |
| EP-2793953-A1 | TELODENDRIMERS WITH ENHANCED DRUG DELIVERY | The Regents of The University of California (US) | 2014-10-29 | — | — | EP | claimed |
| WO-2014093675-A1 | PORPHYRIN MODIFIED TELODENDRIMERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-06-19 | — | — | WO | claimed |
| US-20140161719-A1 | PORPHYRIN MODIFIED TELODENDRIMERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-06-12 | — | — | US | claimed |
| EP-2707419-A2 | REVERSIBLY CROSSLINKED MICELLE SYSTEMS | The Regents of the University of California (US) | 2014-03-19 | — | — | EP | claimed |
| WO-2013096388-A1 | TELODENDRIMERS WITH ENHANCED DRUG DELIVERY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-06-27 | — | — | WO | claimed |
| US-20130164369-A1 | TELODENDRIMER NANODISCS WITHOUT APOLIPOPROTEIN | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-06-27 | — | — | US | claimed |
| WO-2012158622-A2 | REVERSIBLY CROSSLINKED MICELLE SYSTEMS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-11-22 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150045419-A1 | REVERSIBLY CROSSLINKED MICELLE SYSTEMS | CETP, NR1H4, ABCB4 | CYP46A1 107/4885POLA1 3760/4885OSBP 2179/4885 |
| US-20140363371-A1 | TELODENDRIMERS WITH ENHANCED DRUG DELIVERY | NR1H4, CETP, ABCB11 | CYP46A1 51/4885POLA1 4286/4885OSBP 1316/4885 |
| US-20140161719-A1 | PORPHYRIN MODIFIED TELODENDRIMERS | CETP, NR1H4, ABCB4 | CYP46A1 47/4885POLA1 2966/4885OSBP 961/4885 |
| US-20130164369-A1 | TELODENDRIMER NANODISCS WITHOUT APOLIPOPROTEIN | CETP, APOB, LDLR | CYP46A1 1064/4885POLA1 3545/4885OSBP 137/4885 |
| US-11219692-B2 | Porphyrin modified telodendrimers | CETP, NR1H4, ABCB4 | CYP46A1 47/4885POLA1 2966/4885OSBP 961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.